1. Antisecretory activity of plants used to treat gastrointestinal disorders in Mexico
- Author
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Velázquez, Claudia, Calzada, Fernando, Torres, Javier, González, Felipe, and Ceballos, Guillermo
- Subjects
- *
MEDICINAL plants , *MEDICAL botany - Abstract
Abstract: Aqueous and methanolic extracts from 26 medicinal plants used in Mexico to treat gastrointestinal disorders were screened to evaluate their antisecretory activity on cholera toxin-induced intestinal secretion in rat jejunal loops model. Extracts were tested at a dose of 300mg/kg. From 56 samples tested, both extracts from Chiranthodendron pentadactylon, Hippocratea excelsa and Ocimum basilicum were the most potent with inhibition values ranging from 68.0 to 87.6%. On the other hand, the methanolic extract of Geranium mexicanum (aerial parts) and the aqueous extract of Bocconia frutescens showed the highest activity with inhibition values of 93.4 and 86.0%, respectively. The results obtained in this study give some scientific support to the use of the Mexican medicinal plants employed for the treatment of gastrointestinal disorders such as diarrhea. [Copyright &y& Elsevier]
- Published
- 2006
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