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Purpose: The objective of the present article was to evaluate the ımpact of dental midline angulation in asymmetrical faces. Materials and Methods: A full‐portrait image was used to create a set of digitally modified images with a different degree of facial asymmetry, towards the right and the left side of the face respectively. Half of the images were designed with an equivalent angulation of the dental midline in respect to the curve of the lower third of the face and half of them without. Through a web survey, 250 laypeople and 250 orthodontists were asked to assess the attractiveness of each image separately. Results: As the asymmetry of the face was increased, facial attractiveness was further decreased both for laypersons and orthodontists. For each one of the modified images, when the dental midline was following the curve that was formed from the inclination of the simulated asymmetry of the face, the smile attractiveness scores were significantly higher compared to a straight dental midline. Conclusion: Facial asymmetries derived from the inclination of the nose, the chin and the commissural line of the lips can significantly affect the smile attractiveness. An orientation of the dental midline towards the facial asymmetry in order to follow the facial curve, can be beneficial for the smile attractiveness compared to a perpendicular to the face dental midline. During the design of a smile, clinicians have to take into consideration deviations in facial midline, in order their restorations to be in harmony with the rest of the face. Clinical Significance: During the design of a smile, clinicians have to take into consideration deviations in the facial midline, in order their restorations to be in harmony with the rest of the face. [ABSTRACT FROM AUTHOR]

Objective: To investigate whether there is a relationship between the distance between the iris and pupil with the ideal size of buccal corridors. Materials and Methods: A full‐portrait image of a male Caucasian was used to create a set of 11 digitally modified images with different buccal corridor space. A web‐based cross‐sectional study was designed and distributed via an online survey to 200 laypeople and 200 orthodontists to assess image attractiveness, using a Visual analogue scale. For the statistical analysis, Wilcoxon signed‐rank and Mann–Whitney U tests were used. The significance level was set at p < 0.05. Results: The response rate for laypeople was 70% (n = 139), while the rate for orthodontists was 73% (n = 146). For the layperson group, the maximum smile attractiveness score was 10% of buccal width reduction, compared to the iris‐pupillary distance, while for the orthodontists, it was 20%. The attractiveness of the smile was significantly reduced in both groups when the buccal corridor width was increased in comparison to the iris‐pupillary distance. Conclusion: The length between the mesial part of the iris and the distal of the pupil, may constitutes a landmark for the estimation of the desired width of the buccal corridor. Clinical Relevance: Inter iris‐pupillary distance can be the starting point in the smile designing process, in order to perform a facial driven selection of buccal corridor size. [ABSTRACT FROM AUTHOR]