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Your search keyword '"Menezes, Leociley R. A."' showing total 2 results
Start Over Author "Menezes, Leociley R. A." Journal journal of essential oil research
2 results on '"Menezes, Leociley R. A."'

1. Chemical composition and antiparasitic activity of essential oils from leaves ofGuatteria friesianaandGuatteria pogonopus(Annonaceae)

Author

Meira, Cássio S., primary, Menezes, Leociley R. A., additional, dos Santos, Tatiana B., additional, Macedo, Taís S., additional, Fontes, José E. N., additional, Costa, Emmanoel V., additional, Pinheiro, Maria L. B., additional, da Silva, Thanany B., additional, Teixeira Guimarães, Elisalva, additional, and Soares, Milena B. P., additional

Published
2016
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2. Chemical composition and antiparasitic activity of essential oils from leaves of Guatteria friesiana and Guatteria pogonopus (Annonaceae).

Author

Meira, Cássio S., Menezes, Leociley R. A., dos Santos, Tatiana B., Macedo, Taís S., Fontes, José E. N., Costa, Emmanoel V., Pinheiro, Maria L. B., da Silva, Thanany B., Teixeira Guimarães, Elisalva, and Soares, Milena B. P.

Subjects
*ESSENTIAL oils, *ANNONACEAE, *CHEMICAL composition of plants, *ANTIPARASITIC agents, *GAS chromatography/Mass spectrometry (GC-MS), *FLAME ionization detectors
Abstract

Natural products represent a valuable source for discovery of antiparasitic agents. Here, we describe the antiparasitic activity from essential oils extracted from leaves ofGuatteria friesiana(EOGF) andGuatteria pogonopus(EOGP) (Annonaceae). The essential oils were obtained by hydrodistillation and analyzed by GC/MS and GC-FID. The sesquiterpenes are more abundant in both essential oils.G. friesianaare dominated by β-eudesmol (51.9%), γ-eudesmol (18.9%) andα-eudesmol (12.6%). The major compounds identified for EOGP were spathulenol (24.8%), γ-amorphene (14.7%) and germacrene D (11.8%). The essential oils demonstrated potent trypanocidal and antimalarial activities with values of IC50lower than 41.3 μg/mL.EOGF also inhibits the proliferation of amastigotes. In addition, we identified significant ultrastructural alterations induced by the essential oils, especially in the cell membrane, Golgi complex, endoplasmatic reticulum and mitochondria. The results presented herein reinforce the potential of other members of this family for search of antiparasitic compounds. [ABSTRACT FROM AUTHOR]

Published
2017
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