1. Split‐dose 4‐L polyethylene glycol regimen for patients with previous colorectal surgery in bowel preparation before colonoscopy: A randomized, controlled, single‐blind study
- Author
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Yan Zhang, Zhu Liu, Li Xiang Li, Xue Ting Luo, Zhen Li, Yan Qing Li, Chuan Guo Guo, Yue Yue Li, and Ming-Ming Zhang
- Subjects
Male ,medicine.medical_specialty ,Adenoma ,Colorectal cancer ,Colonoscopy ,Polyethylene glycol ,Gastroenterology ,Drug Administration Schedule ,Polyethylene Glycols ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Internal medicine ,PEG ratio ,medicine ,Humans ,Single-Blind Method ,Prospective Studies ,Aged ,medicine.diagnostic_test ,Cathartics ,business.industry ,Middle Aged ,medicine.disease ,Colorectal surgery ,Regimen ,Socioeconomic Factors ,chemistry ,Patient Satisfaction ,Population Surveillance ,030220 oncology & carcinogenesis ,Bowel preparation ,Patient Compliance ,Female ,030211 gastroenterology & hepatology ,Colorectal Neoplasms ,business - Abstract
OBJECTIVE We aimed to investigate the efficacy of a split-dose 4-L polyethylene glycol (PEG) regimen for the quality of bowel preparation in Asian patients with previous colorectal surgery for colorectal cancer (CRC). METHODS This was a prospective, single-center, randomized controlled, endoscopist-blinded study. Patients with previous colorectal surgery for CRC were randomly allocated to a routine, morning-only 2-L PEG (2-MO) group or a split-dose 4-L PEG (4-SD) group. The primary outcome was a successful bowel preparation rate. Secondary outcomes were polyp detection rate (PDR), adenoma detection rate (ADR), patient compliance, satisfaction, tolerance, willingness to repeat the preparation and difficulty of the bowel preparation process. RESULTS In total, 187 patients were included (93 in the 2-MO group, 94 in the 4-SD group) in this study. The rate of successful bowel preparation in the 4-SD group was higher than in the 2-MO group (89.4% vs 66.7%, P
- Published
- 2018