1. Evaluation of the performance of two neutral oral contrast agents in computed tomography enterography: A randomized controlled trial
- Author
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Ming-Ming Zhang, Xiao Yun Yang, Yi Ning Sun, Yue Yue Li, Xiu Li Zuo, Yong Quan Yu, Li Xiang Li, Meng Qi Zheng, Qing Shi Zeng, Rui Ji, and Yan Qing Li
- Subjects
Adult ,Male ,Adolescent ,Nausea ,Digestive System Diseases ,Administration, Oral ,Contrast Media ,polyethylene glycols ,computed tomography enterography ,law.invention ,Young Adult ,03 medical and health sciences ,Quadrant (abdomen) ,0302 clinical medicine ,Randomized controlled trial ,law ,Abdomen ,Intestine, Small ,PEG ratio ,medicine ,Humans ,Mannitol ,In patient ,Aged ,business.industry ,neutral oral contrast ,Gastroenterology ,Original Articles ,Middle Aged ,Computed tomography enterography ,Intestines ,Tolerability ,Patient Satisfaction ,030220 oncology & carcinogenesis ,Female ,Original Article ,030211 gastroenterology & hepatology ,Other ,medicine.symptom ,Tomography, X-Ray Computed ,business ,Nuclear medicine ,small intestine ,medicine.drug - Abstract
Objective To compare the performances, tolerability and acceptability of mannitol and polyethylene glycol (PEG) as oral contrast agents in patients undergoing computed tomography enterography (CTE). Methods Patients aged 18‐75 years indicated for CTE were randomized to receive either mannitol or PEG as contrast agents. The coronal reconstructed images of each abdominal quadrant were assessed for maximum distention, proportion of distended bowel loops, presence of inhomogeneous contents and visibility of the small bowel wall. Overall subjective imaging quality assessment and patients’ tolerability and acceptability were recorded. Results Seventy patients were enrolled and randomized into two groups. In the per‐protocol analysis, no significant differences in imaging quality was found in bowel distention maximum diameter, wall visibility and intestinal homogeneity (all P > 0.05). The mean nausea score was lower in the mannitol group (0 [0‐0] vs 1.0 [0‐3.0], P
- Published
- 2020