1. Clinical utility of botulinum toxin type A local injection therapy for head and forehead hyperhidrosis.
- Author
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Ando Y, Ohshima Y, Yanagishita T, Watanabe H, Tamada Y, Akiyama M, and Watanabe D
- Subjects
- Forehead, Humans, Quality of Life, Sweating, Treatment Outcome, Botulinum Toxins, Type A therapeutic use, Hyperhidrosis drug therapy
- Abstract
Head and forehead hyperhidrosis (HFH) is a disease that causes a large amount of sweating from the head region, and it significantly reduces patients' quality of life. Only a few reports have shown the effectiveness of botulinum toxin type A (BTX-A) local injection therapy (BTX-A therapy) for HFH. To clarify the benefits of BTX-A for HFH, BTX-A therapy was performed in 15 patients, and its efficacy was evaluated. The amount of sweating was measured by the ventilation capsule method and Minor's iodine-starch test. Evaluation was also performed using the Hyperhidrosis Disease Severity Scale (HDSS) and the Dermatology Life Quality Index (DLQI). In most cases, a remarkable antiperspirant effect was observed from 2 weeks after the injection, and the effect lasted for approximately 30 weeks. HDSS and DLQI improved along with the decrease in sweating. Two patients (13.3%) complained of transient mild ptosis. There were no serious side-effects. This study showed that BTX-A therapy is a safe and effective treatment for HFH., (© 2022 Japanese Dermatological Association.)
- Published
- 2022
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