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Your search keyword '"Yuko Hamada"' showing total 13 results
Start Over Author "Yuko Hamada" Journal journal of dermatological science
13 results on '"Yuko Hamada"'

1. The role of High-mobility group box 1 (HMGB1) in Angiosarcoma

Author

Yuko Hamada, Masuzawa Mamiko, Takashi Ueda, Noriko Nemoto, and Yasuyuki Amoh

Subjects
medicine.medical_specialty, High-mobility group, biology, business.industry, medicine, biology.protein, Angiosarcoma, Dermatology, Radiology, HMGB1, business, Molecular Biology, Biochemistry
Published
2017
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2. Human hair-follicle associated pluripotent (HAP) stem cells differentiate to cardiac muscle cells

Author

Sumiyuki Mii, Yuko Hamada, Masateru Yashiro, Robert M. Hoffman, Koya Obama, Nobuko Arakawa, Netsuko Tohgi, Ryoichi Aki, and Yasuyuki Amoh

Subjects
KOSR, Induced stem cells, Amniotic stem cells, Dermatology, Biology, Hair follicle, Biochemistry, Cell biology, Endothelial stem cell, P19 cell, medicine.anatomical_structure, medicine, Stem cell, Molecular Biology, Adult stem cell
Published
2017
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3. Hair follicle associated pluripotent (HAP) stem cell from young mice have the greatest potential to differentiate to cardiac muscle cells

Author

Yuko Hamada, Robert M. Hoffman, Sumiyuki Mii, Aiko Yamazaki, Katsumasa Kawahara, Yasuyuki Amoh, Masateru Yashiro, Nobuko Arakawa, and Ryoichi Aki

Subjects
medicine.medical_specialty, Pathology, medicine.anatomical_structure, Endocrinology, Internal medicine, medicine, Cardiac muscle, Dermatology, Stem cell, Biology, Hair follicle, Molecular Biology, Biochemistry
Published
2017
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4. From hair to heart: Nestin-expressing hair follicle associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells

Author

Katsumasa Kawahara, Robert M. Hoffman, Ryoichi Aki, Yuko Hamada, Yasuyuki Amoh, Nobuko Arakawa, Masateru Yashiro, and Sumiyuki Mii

Subjects
chemistry.chemical_classification, Cardiac muscle, Dermatology, Anatomy, Biology, Nestin, Hair follicle, Biochemistry, Regenerative medicine, Cell biology, Follicle, medicine.anatomical_structure, chemistry, Keratin, medicine, sense organs, Stem cell, Molecular Biology, Spinal Cord Regeneration
Abstract

We have previously demonstrated that the neural stem-cell marker nestin is expressed in hair follicle stem cells located in the bulge area which are termed hair-follicle-associated pluripotent (HAP) stem cells. HAP stem cells from mouse and human could form spheres in culture, termed hair spheres, which are keratin 15-negative and CD34-positive and could differentiate to neurons, glia, keratinocytes, smooth muscle cells, and melanocytes in vitro. Subsequently, we demonstrated that nestin-expressing stem cells could effect nerve and spinal cord regeneration in mouse models. In the present study, we demonstrated that HAP stem cells differentiated to beating cardiac muscle cells. We separated the mouse vibrissa hair follicle into 3 parts (upper, middle, and lower), and suspended each part separately in DMEM containing 10% FBS. All three parts of hair follicle differentiated to beating cardiac muscle cells as well as neurons, glial cells, keratinocytes and smooth muscle cells. The differentiation potential to cardiac muscle is greatest in the upper part of the follicle. The beat rate of the cardiac muscle cells was stimulated by isoproterenol and inhibited by propanolol. HAP stem cells have potential for regenerative medicine for heart disease as well as nerve and spinal cord repair.

Published
2016
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6. 066 Anti-tumor activity of IL-12 against angiosarcoma

Author

Yuko Hamada, T. Fuiimura, Mikio Masuzawa, S. Nishivama, N. Hara, and Kensei Katsuoka

Subjects
Antitumor activity, business.industry, Interleukin 12, Cancer research, Medicine, Angiosarcoma, Dermatology, business, Molecular Biology, Biochemistry
Published
1997
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10. The investigation of phospholipids and fatty acid of red blood cell (RBC) membrane and serum in patients with atopic dermatitis (AD)

Author

Shojiro Tsukamoto, Yuko Hamada, Hiroshi Takasu, Shigeo Nishiyama, Kensei Katsuoka, Nagoya T, and Akira Fujioka

Subjects
chemistry.chemical_classification, medicine.medical_specialty, Chemistry, Fatty acid, Dermatology, Atopic dermatitis, medicine.disease, Biochemistry, Rbc membrane, Red blood cell, Endocrinology, medicine.anatomical_structure, Internal medicine, medicine, In patient, Molecular Biology
Published
1993
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