1. Perineural Invasion in Head and Neck Cancer.
- Author
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Schmitd, L. B., Scanlon, C. S., and D'Silva, N. J.
- Subjects
HEAD & neck cancer treatment ,CANCER invasiveness ,CONDUCTION anesthesia ,SQUAMOUS cell carcinoma ,DISEASE prevalence ,BIOLOGICAL crosstalk - Abstract
Perineural invasion (PNI) is a mechanism of tumor dissemination that can provide a challenge to tumor eradication and that is correlated with poor survival. Squamous cell carcinoma, the most common type of head and neck cancer, has a high prevalence of PNI. This review provides an overview of clinical studies on the outcomes and factors associated with PNI in head and neck cancer and on findings on cancer-nerve crosstalk. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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