1. Determination of capillary hemoglobin levels using the HemoCue system in intensive care patients
- Author
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Agathe Kleiber, Yannick Mallédant, Charles Chanavaz, Philippe Seguin, Jeff Morcet, Foie, métabolismes et cancer, Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Service d'anesthésie réanimation chirurgicale [Rennes], Université de Rennes (UR)-Hôpital Pontchaillou, Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Hôpital Pontchaillou-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), and Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)
- Subjects
Male ,medicine.medical_specialty ,Pediatrics ,Fingerstick ,Critical Illness ,Point-of-Care Systems ,Surgical intensive care unit ,Hemoglobin levels ,Critical Care and Intensive Care Medicine ,Gastroenterology ,Hemoglobinometer ,03 medical and health sciences ,Hemoglobins ,0302 clinical medicine ,HemoCue ,030202 anesthesiology ,Intensive care ,Internal medicine ,medicine ,Automated analyzer ,Hemoglobin measurement ,Humans ,030212 general & internal medicine ,Prospective Studies ,HEMOGLOBINOMETER ,MESH: Capillaries ,MESH: Hemoglobinometry ,MESH: Humans ,MESH: Middle Aged ,Adult patients ,business.industry ,Anemia ,[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology ,Middle Aged ,MESH: Prospective Studies ,MESH: Male ,MESH: Point-of-Care Systems ,3. Good health ,Capillaries ,Intensive Care Units ,MESH: Hemoglobins ,MESH: Critical Illness ,Hemoglobinometry ,MESH: Intensive Care Units ,Female ,Hemoglobin ,business ,MESH: Female - Abstract
International audience; PURPOSE: The study aimed to compare hemoglobin (Hb) values determined using the portable HemoCue system (HemoCue Hb 201+; HemoCue AB, Ängelholm, Sweden) with laboratory Hb level determination. MATERIALS AND METHODS: Adult patients hospitalized in our surgical intensive care unit who required an Hb level determination were included. To determine Hb level, one drop of arterial (A) or venous (V) blood was analyzed using HemoCue (HemoCue([A/V])), and also with an automated analyzer in the laboratory (Hb reference method, or Hb Lab([A/V])). Capillary blood (Cap) sample obtained simultaneously by fingerstick was analyzed using HemoCue (HemoCue([Cap])). Factors that could interfere with the accuracy of fingerstick measurements were also studied. Paired Hb level measurements were compared by Bland and Altman analysis (Hb Lab([A/V]) vs HemoCue([A/V]) and HemoCue([Cap])). RESULTS: One hundred fifty blood samples were obtained from 79 patients. The mean absolute differences between Hb Lab [A] and HemoCue [A], Hb Lab [V] and HemoCue [V] and Hb Lab [A/V] and HemoCue [Cap] were 0.1 g/dl (95% confidence interval, -1.9 to + 2.2 g/dl), 0.1 g/dl (95%CI, -2.5 to +2.6 g/dl) and 1.1 g/dl (95%CI, -3.6 to + 5.8 g/dl, respectively. Edema was the sole independent risk factor for discordance between HemoCue([Cap]) and Hb Lab([A/V]) (odds ratio, 6.65; 95% CI, 1.99-22.21; P < .001]. CONCLUSIONS: Hemoglobin level determination using HemoCue should not be used in critically patients, especially when capillary blood samples are used and/or in presence of edema.
- Published
- 2010
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