Search

Background: In 2018, the first device to use high-intensity focused electromagnetic (HIFEM) technology to non-invasively build muscle was brought to market. Even more recently, the first HIFEM and radiofrequency combination device designed to both build muscle and eliminate fat cells came into use (HIFEM+). In view of the increase in recently published original data pertaining to HIFEM, an advisory board recently convened to discuss the group's clinical experiences with this technology., Aim: Communicate an advisory group's recommendations for the current use of HIFEM+ technology for aesthetic indications., Methods: An advisory board meeting to discuss challenges and opportunities for HIFEM devices in aesthetic medicine took place in November 2020, via remote conference. The expert advisory board consisted of a group of senior aesthetic physicians regularly treating patients with non-invasive body contouring devices. A narrative review of the literature and key recommendations from the meeting are presented herein., Results: To date, the combined results of several clinical studies (including over 500 patients and 30 investigators) support that patients treated with HIFEM+ experience on average, 30% less fat, 25% more muscle, 19% reduction in abdominal separation and up to 5.9 cm reduction in waist circumference. Moreover, HIFEM+ induces a 30% increase in satellite cell content, which is similar to the 36% increase observed following twelve weeks of exercise., Conclusions: The advisory board unanimously agreed on several messages related to HIFEM technology, including that the pairing of HIFEM and radiofrequency (HIFEM+) enables a higher intensity of muscle stimulation and lipolysis, compared to HIFEM alone., (© 2021 Wiley Periodicals LLC.)

Background: Aesthetics medicine, a controversial branch of clinical medicine known for its high degree of commercialization, faces numerous conflicts, particularly in some developing countries. The global aesthetics medicine industry requires enhancements of its legal and supervision framework and risk management systems. Aims: This paper aimed to provide a comprehensive visual analysis of academic achievements related to regulatory and legal issues in the field of aesthetic medicine and to identify its development trends and research hotspots. Methods: The Web of Science Core Collection was employed to retrieve relevant studies, resulting in a total of 602 research articles after selection. Utilizing bibliometric methods and CiteSpace, this study analyzed the primary countries, institutions, authors, journals, hotspots, frontiers, and trends in this domain. Results: The findings indicated rapid increases in the number of published papers. The United States emerged as the leading contributor with 131 research papers and the highest intermediate centrality. Eleven keyword clusters were identified, with "adolescence" and "office‐based surgery" being the most recent topics. We also analyzed the trends and frontiers of legal research in medical aesthetics. Conclusion: The importance of informed consent has been increasingly emphasized, and research in the field of medical aesthetics has been gradually expanding beyond individual cosmetic procedures. The management system has become more comprehensive, moreover, guidelines and medical laws have been continually published, with research shifting toward a holistic perspective that encompasses patients, medical aesthetic providers, and regulatory authorities in the study of medical aesthetics regulation and legislation. This paper also proposes some innovative directions for future research and applications. [ABSTRACT FROM AUTHOR]

The May 2024 issue of the Journal of Cosmetic Dermatology offers cutting-edge research papers and review articles in the field of cosmetic dermatology. The journal prides itself on its efficient peer-review process, with associate editors assigning papers to reviewers who provide recommendations for acceptance, editing, or rejection. The journal aims to provide authors with timely responses and invites readers to get involved in the review process. The journal also acknowledges the hard work of its publishers and the team that keeps everything organized. [Extracted from the article]

Background: Pigment Red 53 is a dangerous synthetic dye that is often added to cosmetics, even though its use in cosmetic products has been prohibited because of possible impacts on health. Faster and more sensitive detection of Pigment Red 53 is needed for onsite analysis to protect the community from illegal cosmetics that contain the dye. Indicator color charts are a kind of analytical method that can be used to detect Pigment Red 53 in cosmetic products, including lipstick, rouge, and eyeshadow. Such charts are practical, fast, and can be used for onsite analysis. Methods: In this study, an indicator for Pigment Red 53 detection was obtained through a reagent reaction that caused a specific color change. An indicator color chart was then produced by setting out in paper form the series of colors which resulted from the reaction of specific chemical reagents and Pigment Red 53 solutions at concentrations of 10, 20, 40, 60, 80, and 100 ppm. Results: The testing results showed that the indicator color chart may be used as an initial screening method for the detection of Pigment Red 53 in cosmetic products with a detectable minimum concentration of 10 ppm. Out of nine samples, only one (Eyeshadow 3) tested positive for Pigment Red 53. Further analysis was carried out on the indicator color chart and the results showed good agreement with TLC and UV–Vis spectrophotometry methods. Conclusion: The results reported in this paper demonstrate that the indicator color chart is a good prospective method for onsite analysis to detect Pigment Red 53 in cosmetic samples, with a lower detection limit compared to polymer‐based indicators. [ABSTRACT FROM AUTHOR]

Background: The increasing popularity of cosmetic injections using various fillers and neuromodulators for facial rejuvenation has brought both new opportunities and challenges to this field. Aim: Our study was designed to employ bibliometric and visual analysis for a qualitative and quantitative evaluation of facial cosmetic injections, as well as to identify research trends and hotspots in this field. Methods: All publications covering facial cosmetic injection during 2002–2023 were retrieved and extracted from the Web of Science database. The VOSviewer 1.6.18 software and the online tool (http://bibliometric.com/) were applied to analyze the publication trend. Results: A total of 3797 articles related to facial cosmetic injection were identified during the period 2002–2023. The United States had the largest volume of publications (1520, 40.0%), followed by China (333, 8.8%) and Germany (282, 7.3%). Among the institutions and journals, the University of California system and Plastic and Reconstructive Surgery accounted for the most papers related to facial cosmetic injection, respectively. Facial anatomy and injection techniques, prevention and management of complications, regenerative medicine, efficacy and safety of various soft‐tissue fillers, as well as botulinum toxin injections for facial rejuvenation were identified as hotspots for facial cosmetic injections. Conclusions: Facial cosmetic injections are showing an increasing trend in terms of both the number of published papers and operations performed. Despite the notable advancements in this field, numerous challenges persist, including safety concerns and the level of research evidence. With the emergence of novel technologies and materials, scholars from diverse countries and institutions should engage in more extensive collaboration, thereby directly expediting the progress of this field. [ABSTRACT FROM AUTHOR]

Background: To assess the effect and safety of probiotics for treating urticaria. Methods: Randomized controlled trial (RCT) papers on the probiotics treatment published before May 2019 were retrieved from various databases like PubMed, EMbase, MEDLINE (Ovid), SCI‐Hub, Springer, ClinicalKey, VIP, and CNKI. The treatment plan that we include are oral administration of single probiotic, multiple probiotics, and the combination of probiotics and antihistamines. Meta‐analysis of the data was performed by RevMan 5.3 software. Results: A total of nine RCT papers were included: four papers for oral administration of single probiotic, three papers for oral administration of multiple probiotics, and two papers for oral administration of a probiotic combined with antihistamines. The results of meta‐analysis showed that the therapeutic effect of the probiotic group was significantly higher than the control group (placebo or antihistamines) (RR = 1.09, 95% CI: 1.03–1.16, p = 0.006). And compared with the placebo group, the therapeutic effect of single probiotic group was significantly improved (RR = 1.11, 95% CI: 1.01–1.21, p = 0.03). Regarding therapeutic effect, there was no statistically significant difference between the multiple probiotics group and placebo group (RR = 1.00, 95% CI: 0.94 ~ 1.07, p = 0.91); the therapeutic effect of single probiotic combined antihistamine group was significantly higher than the antihistamine group (RR = 1.13, 95% CI: 1.07–1.19, p < 0.0001). Regarding the incidence of adverse reactions, there was no significant difference between the probiotic group and the control group (p = 0.46). Conclusion: The treatment plan of oral administration of probiotics has significant therapeutic effects on urticaria, but the therapeutic effects of the administration of multiple probiotics and the safety of probiotic therapy are still not yet obvious. Some large‐scale, multi‐centered RCT studies are needed in the future for clarification. [ABSTRACT FROM AUTHOR]

The June 2024 issue of the Journal of Cosmetic Dermatology highlights the current state of aesthetic and cosmetic dermatology, with global aesthetics meetings experiencing high attendance and a focus on in-person knowledge sharing. The journal operates on a peer-reviewed process, where each manuscript is reviewed by at least two reviewers and then decided upon by an associate editor. The editor expresses gratitude for the submissions and discusses the journal's commitment to treating each paper fairly and equally. The journal also aims to continue improving its Impact Factor. [Extracted from the article]

Background: Androgenetic alopecia (AGA) is a prevalent form of hair loss that affects both men and women, severely impacting patients' quality of life. Traditional treatments include oral medications, topical medications, and hair transplantation, but these methods have certain side effects and limitations. How to safely effectively and maximally promote hair growth has been a key issue in the treatment of AGA. In recent years, fractionated laser therapy, as a noninvasive method, has gradually gained attention due to its minimally invasive and highly effective nature. Aims: In this paper, we summarized the studies related to fractional laser treatment of AGA in the past 15 years, and discussed its therapeutic mechanism, clinical effect, future development direction, and advantages and disadvantages compared with traditional treatment methods in the treatment of AGA. Methods: An extensive literature search was conducted using PubMed, Google, Google Scholar, Embase, and Scopus. All available articles studying fractional laser treatment of AGA were compiled in March 2024. Titles and abstracts were then screened for relevance and thoroughly examined for patient clinical outcomes. Prospective clinical trials, retrospective chart reviews, case series, and individual case reports were included in the literature review. Conclusions: Fractional laser treatment of AGA showed remarkable efficacy and high safety. Compared with traditional treatments, fractional laser has the advantages of minimally invasive, quick recovery, fewer side effects, and a wide range of population applicability, providing an effective treatment option for AGA patients. Further large‐scale clinical studies will help optimize the laser parameters and treatment settings to improve the therapeutic effect. [ABSTRACT FROM AUTHOR]

Background: Cosmetic dermatology is a growing field as more patients are seeking treatments for esthetic concerns. Traditionally, practitioners and patients utilize their own perceptions, current beauty standards, and manual observation to determine their satisfaction with cosmetic interventions. Artificial intelligence (AI) can be introduced into cosmetic dermatology to provide objective data‐driven recommendations to both dermatologists and patients. Objective: The purpose of this paper is to compose a unified review that illustrates the various facets of artificial intelligence and formulate a hypothesis regarding the new implications of artificial intelligence in cosmetic dermatology specifically. Methods: A comprehensive search on PubMed was conducted to identify the available information related to AI in cosmetic dermatology. The search was conducted using a combination of keywords including "cosmetic dermatology" and "artificial intelligence." Results: The current literature indicates that AI models offer personalized, efficient, and result‐driven outputs that can enhance cosmetic outcomes, patient satisfaction, and overall experience. Conclusion: Artificial intelligence integration in cosmetic dermatology shows a promising future, offering the ability to analyze vast data sets and deliver a tailored patient experience. By incorporating AI into cosmetic dermatology, there is an opportunity to balance evidence‐based decision‐making with the artistic human touch of cosmetic dermatologists. [ABSTRACT FROM AUTHOR]

Introduction: Laser technology has fundamentally transformed the landscape of dermatology, offering nuanced solutions for skin rejuvenation and resurfacing. This paper aims to explore the spectrum of laser technologies, from ablative to non‐ablative and fractional lasers, their mechanisms, benefits, and tailored applications for diverse skin conditions. As we delve into the intricacies of each technology, we also consider the scientific advancements that have made these treatments safer and more effective, promising a new horizon in skin rejuvenation. Objective: This comprehensive analysis seeks to evaluate recent advancements in laser technology for skin rejuvenation, focusing on efficacy, safety, and patient satisfaction. Methods: The selection criteria for studies in this publication focused on recent, peer‐reviewed articles from the last 20 years, emphasizing advancements in laser technologies for skin rejuvenation. Our comprehensive review involved searches in PubMed, Cochrane, Scopus and Google Scholar using keywords like "skin rejuvenation," "laser technology," "efficacy," "safety," and "dermatology." This approach focused on inclusion of recent research and perspectives on the efficacy and safety of laser treatments in the field of dermatology. Results: Our literature review reveals advancements in laser skin resurfacing technologies, notably fractional lasers for minimal downtime rejuvenation, ablative lasers for precise tissue vaporization, and non‐ablative lasers for coagulation effect promoting collagen with reduced recovery. Hybrid and picosecond lasers are highlighted for their versatility and effectiveness in addressing a wide array of skin concerns. The findings also emphasize the development of safer treatment protocols for ethnic skin, significantly reducing risks like hyperpigmentation and scarring, thus broadening the scope of effective dermatological solutions. Conclusion: This extensive review of advancements in laser technologies for skin rejuvenation underscores a remarkable evolution in dermatological treatments, offering an expansive overview of the efficacy, safety, and patient satisfaction associated with these interventions. Furthermore, the exploration of combination treatments and laser‐assisted drug delivery represents a frontier in dermatological practice, offering synergistic effects that could amplify the therapeutic benefits of laser treatments. [ABSTRACT FROM AUTHOR]

ABSTRACT Background Aims and Methods Results Conclusions With the ever‐changing cosmetic landscape, Ayurvedic skincare, rooted in the holistic medical system of Ayurveda from India, has gained popularity in Western countries due to its natural ingredients and multipurpose benefits. Originating from the earth's sources, such as plants and minerals, each ingredient like ashwagandha, turmeric, and neem among others are believed to address various cosmetic and medical issues.Despite centuries of anecdotal evidence, modern clinical trials validating these claims are limited. This paper looked to investigate current literature regarding Ayurvedic skincare and promote its continued research.Existing in vitro studies have demonstrated significant potential, indicating the need for further large‐scale testing. The rise of Ayurvedic ingredients is partially driven by the increasing cost of healthcare and the belief in the superiority of natural self‐medication. However, healthcare providers must educate patients on the potential dangers of relying solely on natural products. Products like concentrated lemon juice or homemade sunscreens lack scientific validation and have been implicated in various cosmetic and medical issues, highlighting the need to prevent misinformation and improve education from trusted sources.This paper explores the current literature that establishes promising prospects for Ayurvedic skincare, emphasizing the need for quality control and clinical trials, and highlights how Ayurvedic medicine, as it modernizes, holds the potential to become a major player in cosmetic dermatology. [ABSTRACT FROM AUTHOR]

Background: Cryolipolysis, also known as fat freezing, is a nonsurgical technique specialized for localized fat reduction. Utilizing targeted cold exposure to adipose tissue, cryolipolysis devices induce cellular apoptosis in adipocytes while sparing surrounding tissues, resulting in the selective disruption of fat cells and subsequent removal of damaged cells by macrophages. A reduction of the fat layer produces a noninvasive cosmetic benefit that provides an accessible alternative to liposuction. Objective and subjective measurements have demonstrated significant reduction in fat volume and high patient satisfaction rates. Cryolipolysis has been proven to be safe with minimal adverse effects. However, further research is needed to fully understand the mechanism of cryolipolysis and its efficacy in different treatment areas. This paper aims to provide a comprehensive overview of cryolipolysis, including its mechanism of action, indications, contraindications, adverse effects, results and outcomes, safety profile, and areas requiring further research. Methods: Our primary phase of literature review consisted of a PubMed search looking for all published literature around cryolipolysis. We employed a review approach that examined over 30 papers with the key search terms of "cryolipolysis," "fat‐freezing," "cosmetic dermatology," "body contouring," "adverse effects," "adipocyte apoptosis," "Coolsculpting®," "cold panniculitis," and "localized fat reduction." We then analyzed each paper, extracting relevant information to gain a multidimensional understanding of cryolipolysis to provide a comprehensive review. Conclusion: Cryolipolysis, with its ability to target and reduce localized adipose tissue, has emerged as a promising nonsurgical technique in the field of body contouring. It offers patients a valuable option for achieving their desired fat reduction without the need for a lengthy recovery period or major surgery. Cryolipolysis has shown to reduce the number of adipocytes in the treated area, a phenomenon that can be objectively quantified through various means, including fat caliper measurements, ultrasound assessments, and 3D imaging, or subjectively observed through patient satisfaction rates, clinical observations, and investigator assessments. In addition to its effectiveness in reducing localized adipose tissue, cryolipolysis also holds potential in the area of skin tightening. Preliminary studies suggest that cryolipolysis may have a positive impact on skin elasticity and tightening. Further investigation of this mechanism is needed to provide a better understanding of its potential in achieving optimal cosmetic outcomes for patients. By combining the benefits of fat reduction and skin tightening, cryolipolysis has the potential to offer a comprehensive nonsurgical solution for body contouring. [ABSTRACT FROM AUTHOR]

Background: Adipose tissue is a vital metabolic organ that takes part in body homeostasis. However, an increase in fat tissue can be detrimental for one's health and lead to undesirable changes in body shape. Noninvasive lipolysis is becoming an increasingly popular method to destroy and remove excess body fat and improve one's satisfaction with their body appearance. Aim: The aim of this study was to perform an evidence‐based review of the clinical efficacy and safety of noninvasive lipolysis modalities in fat reduction. Materials and Methods: An evidence‐based review was performed to evaluate the scientific evidence available on the subject. Three electronic databases (PubMed, Scopus, and Embase) were searched between February and May 2022 for randomized controlled trials and observational studies performed on adult population in the last 20 years investigating the clinical outcomes of noninvasive lipolysis modalities. The selected studies were divided by modality type (cryolipolysis, ultrasound therapy, radiofrequency, and laser therapy), and the data on the efficacy and safety were extracted. Results: In total, the search identified 55 papers which met the inclusion criteria. All four energy‐based modalities, including cryolipolysis, ultrasound therapy, radiofrequency, and laser therapy, were shown to be clinically effective in terms of both objective body measurements, such as fat layer thickness or circumference reduction, and subjective patient satisfaction. Furthermore, the abovementioned methods were proven to have a low side effect profile. Conclusion: In conclusion, although evidence supports safety and efficacy, further well‐designed trials are needed to strengthen confidence in long‐term effectiveness and safety of noninvasive lipolysis. [ABSTRACT FROM AUTHOR]

Background: In recent years, there has been a rise in non‐surgical rhinoplasty (NSR) due to its minimally invasive approach. As with all procedures, NSR can result in complications. Although rare, the consequences of complications can result in a devastating outcome and therefore an evidence‐based approach to enable the recognition and management of NSR complications is required. Aims: This paper aims to review and appraise current literature to determine the evidence base for complications experienced with NSR including their causes and management. Methods: A systematic review was conducted using a PRISMA methodology. The PubMed and WebofScience databases were queried. Papers relating to the three most commonly used filler materials; hyaluronic acid (HA), calcium hydroxyapatite and collagen were collated. Results: Four hundred and ninety studies were identified in the initial literature search and after applying an inclusion and exclusion criteria, 12 papers were included. Conclusion: The results of this literature review showed a paucity of high‐level evidence which may indicate underreporting of NSR complications. Although treatment is not always effective, it is clear that early recognition and treatment favors better outcomes with the potential for complete resolution in some cases. Immediate availability of hyaluronidase is important when undertaking NSR with HA as this review showed early use was critical in the management of serious complications such as vascular occlusion. [ABSTRACT FROM AUTHOR]

Background: Botulinum toxin has been widely and mainly used for the treatment of conditions affecting the upper and middle face; however, recent efforts have expanded the indications of botulinum toxin injection to the lower face and neck areas for cosmetic and medical purposes. Aims: We have reviewed the latest updates on using botulinum toxin in the lower face and neck focusing on cosmetic purposes and have discussed the existing concerns as well as the adverse sequelae of these newer indications. Patients/Methods: A comprehensive literature search was performed using the following keywords [[botulinum] AND [[Toxin] OR [Neurotoxin]]] AND [[Lower AND Face] AND/OR [Neck]] within the main databases including Web of Science, PubMed, Embase and gray literature on and before February 2023. The data were screened using titles and abstracts and those relevant to the topic were included in the paper. Results: Botulinum toxin injection has considerable cosmetic and therapeutic effect on facial contouring, masseteric hypertrophy, lower face and neck scars, gummy smile, drooping lip corner and even skin rejuvenation. Conclusion: BNT injection has been widely used for the treatment of different medical and cosmetic purposes. Low rates of side effects, which were self‐limited in most cases, have been reported in the literature, making BNT a safe therapeutic medication in most cases. However, regulatory status needs to be updated and more accurately revised in many countries and more comprehensive research is required to address the existing gaps in this area including the site, dosage, and method of injection in each case. [ABSTRACT FROM AUTHOR]

Background There is a lack of studies objectively comparing the efficacy of topical antiperspirants in reducing sweat. Objective To objectively and quantitatively compare the efficacy of two aluminum salt solutions for the reduction of induced sweating. Methods A subject, rater, and statistician-blinded, randomized, controlled trial. Nineteen subjects were exposed to a standardized heat challenge for 3 h. Topical agent A (20% aluminum chloride hexahydrate) was randomized to either axilla, and topical agent B (1% aluminum acetate) assigned to the contralateral side. A sauna suit induced sweating during three 30-min heat intervals: (1) with no study agents (pre); (2) with both study agents, one on each side; and (3) after the agents were washed off (post). Sweat levels were measured by securing Whatman® filter paper to each axilla and measuring the paper weight after each heat interval. The difference in paper weight following each heat interval between Study Agent A and Study Agent B was measured by a gravimetric scale. Results Topical agent A had a significantly greater effect at reducing axillary sweating than B (P = 0.0002). Conclusion In a sweating simulation, 20% aluminum chloride hexahydrate quantitatively and objectively appeared to reduce sweat more effectively than 1% aluminum acetate. [ABSTRACT FROM AUTHOR]

Background: Our bodies are a collection of nutrients. For healthy body production and activities, good nutrients must be balanced and supplied steadily. However, as modern people eat more irregular meals and fast food, they are running out of nutrients needed by the human body. As a result, research was conducted on the effect of eggs with good cost‐effectiveness on the human body and hair. Purpose: The purpose of this paper is to review the literature investigated to convey knowledge of the positive nutrients of modern people's nutrition and eggs. Methods: These data were reviewed to identify agreement between each section and the unique guiding area. Regarding the survey criteria, it was finally decided that 31 papers were suitable for evaluating the purpose of research as follows. PRISMA flowcharts allow you to determine the number of records identified, included, and excluded. Results: Eggs are considered the most cost‐effective foods that deliver protein, biotin, choline, and vitamin A to the world, and eggs that can be easily consumed are known as nutritional foods because they contain protein, lipids, minerals, and embryonic development growth factors. It is widely consumed as a food that can be eaten by anyone, including the elderly and children. Conclusions: In this study, eggs can be used as important data for modern people by delivering nutrients to the human body and hair of modern people and understanding positive nutrients. [ABSTRACT FROM AUTHOR]

ABSTRACT Background Methods Results Conclusion Systematic Review Registration Recently, numerous topical products containing plant‐based ingredients have been reported to resist skin aging. However, there is a lack of sufficient evidence to substantiate these claims. This paper presents a comprehensive review and meta‐analysis to evaluate the efficacy and safety of topical products containing plants or plant extracts in anti‐aging.Four databases—PubMed, Embase, Web of Science, and the Cochrane Library (CENTRAL)—were systematically searched for articles related to plant‐based interventions and skin aging, covering the period from January 2000 to December 2024. A total of eight randomized controlled trials (RCTs) met the inclusion criteria and were included in the meta‐analysis.Products containing plant extracts demonstrated a statistically significant difference in improving skin hydration and skin elasticity, reducing melanin and erythema compared to other products. No significant statistical difference was observed in reducing transepidermal water loss (TEWL). Subgroup analysis revealed a significant statistical difference in improvement overall skin elasticity (R2) during short‐term (≤ 8 weeks)treatments, while no statistical difference was observed during long‐term (> 8 weeks)treatments. Additionally, no significant difference was observed in the specific measurements of skin elasticity, including R5 (net elasticity) and R7 (the ratio of elastic recovery to total deformation). Regarding safety, no adverse events were reported in six studies, while the remaining two studies did not specify whether adverse events occurred.The meta‐analysis results indicated that botanical preparations significantly enhanced skin hydration, reduced melanin levels and erythema, and increased overall skin elasticity. However, the analysis did not provide sufficient evidence to support a reduction in transepidermal water loss (TEWL), or improvements in R5 (net elasticity) and R7 (the ratio of elastic recovery to total deformation).PROSPERO (york.ac.uk) identifier: CRD42023478803 [ABSTRACT FROM AUTHOR]

ABSTRACT Background Aim Methods Results Conclusion Energy‐based photoelectric and ultrasonic devices are essential for skin rejuvenation and resurfacing in the field of plastic surgery and dermatology. Both functionality and appearance are impacted by factors that cause skin to age, and various energy types have variable skin penetration depths and modes of transmission.The objective is to advise safe and efficient antiaging treatment while precisely and sensitively controlling and assessing the extent of thermal damage to tissues caused by different kinds of energy‐based devices.A literature search was conducted on PubMed to review the mechanisms of action and thermal effects of photoelectric and ultrasonic devices in skin remodeling applications.This paper reviews the thermal effects of energy‐based devices in skin resurfacing applications, including the tissue level and molecular biochemical level. It seeks to summarize the distribution form, depth of action, and influencing factors of thermal effects in combination with the mechanisms of action of various types of devices.Accurate control of thermal damage is crucial for safe and effective skin remodeling treatments. Thorough investigation of molecular biochemical indicators and signaling pathways is needed for real‐time monitoring and prevention of severe thermal injury. Ongoing research and technological advancements will improve the accuracy and control of thermal damage during treatments. [ABSTRACT FROM AUTHOR]

Objective: To review the technique and outcomes of using dermal filler to camouflage forehead osteoma, providing a minimally invasive alternative to surgical excision. Background: Forehead osteoma, commonly known as a forehead bump or bone spur, can be a cosmetic concern. Surgical excision, while effective, carries risks of scarring and postoperative complications. An innovative approach using dermal filler offers a potential solution. Methods: A hyaluronic acid‐based filler is injected into the deep subcutaneous plane over the bony prominence using a cannula. The fanning technique ensures even distribution of the filler. The procedure's safety, patient selection, and communication between the injector and patient are emphasized to achieve optimal results. Results: The technique provides immediate aesthetic improvement with results that can last up to 12 months, depending on the filler used. While generally safe, potential complications include infections, swelling, asymmetry, and lumpiness. Proper technique, patient selection, and good communication between the injector and patient are critical to achieving optimal outcomes. Conclusion: Using dermal filler to camouflage forehead osteoma is a minimally invasive alternative to surgical excision, offering immediate and long‐lasting results with minimal downtime and fewer risks. Further studies are needed to refine the technique and optimize outcomes. [ABSTRACT FROM AUTHOR]

Objective: Using bibliometric methods, this study analyzed and summarized the current situation and development of the global application of botulinum toxin in dermatology. Methods: Literature published in the Web of Science Core Collection database from January 1, 2000 to October 28, 2023 was searched for topics such as "Botulinum toxin," "Dermatology," and so forth. The number of publications, countries, institutions, journals, authors, cited literature, keywords, and so forth, were analyzed and a visual knowledge map was created using scientometric tools such as CiteSpace, VOSviewer, and Scimago Graphica. Results: A total of 2039 documents were retrieved and 1877 documents were included after de‐duplication and transformation. The country with the highest number of published periodical articles was the United States; the main research institution was Yonsei University; the author with the highest number of published periodical articles was Kim, Hee Jin; and the high‐frequency keywords mainly related to indications, combination therapy, and safety optimization. Conclusion: The results of this study provide information on the current status and trends in clinical studies of botulinum toxin in dermatology, which will help researchers identify hotspots and explore new research directions in this field. [ABSTRACT FROM AUTHOR]

Background: As we enter the era of long COVID, recent studies on the relationship between coronavirus disease‐19 (COVID‐19) and skin are being conducted from various angles. Awareness of the safety of healthy skin is increasing. Objectives: Therefore, in this study, we empirically analyzed safe cosmetics, natural cosmetics, and organic cosmetics, which have recently become a critical issue. Methods: Keywords such as 'long COVID', 'COVID‐19 Skin', 'ISO Natural Organic Index', 'edible', 'safe cosmetics', 'natural cosmetics', and 'organic cosmetics' were searched and created. This study was conducted using PubMed, Google Scholar, Riss, Scopus, and ResearchGate. Accordingly, a total of 689 papers were studied. This paper was successfully completed using a total of 41 references in this study using PRISMA flow diagram. Results: In the long COVID era, customers in the beauty and cosmetics market will have to apply ISO natural organic ingredients to the cosmetics and beauty industry, reflecting consumer demand for edible ingredients for safety issues. Therefore, it will be able to provide new strategy and implications for a safer cosmetic market that values health and beauty. Conclusion: Therefore, in this literature review, interest in skin has increased due to the long corona, and it was determined that changes in the cosmetic market would be necessary by using the ISO natural organic index for the consumer's desire for healthy skin. Therefore, in this article, in the future development of eco‐friendly organic cosmetics, in line with the natural and environment‐friendly changes reminiscent of the efficacy or ingredients of products, it is necessary to develop cosmetics using the ISO natural organic index that meets the needs of consumers and a differentiated strategy. [ABSTRACT FROM AUTHOR]

Background: Consumer and advanced consumption culture in modern society is an era that focuses on individual personality and value, and "my own customized products", or customized marketing strategies, are actively being developed throughout the industry. Recently, IT technologies that can support personalized services such as artificial intelligence, ubiquitous systems, and marketing automation have been recognized for their potential, directly or indirectly affecting distribution industries affected by personal consumption culture. Accordingly, customized products or services, i.e., customization, are attracting attention as an effective methodology to cope with such market changes. Objectives: Among the necessities used by modern women, cosmetics account for an endless interest in beauty and maintaining physical and mental health, and as the cosmetics market expands, it is considered that the cosmetics industry needs a clearer and in‐depth study on the cosmetics submarket to satisfy consumers' diverse needs. Methods: This review paper is a literature review, and a narrative review approach has been used for this study. A total of 300 to 400 references were selected using representative journal search websites such as PubMed, Google Scholar, Scopus, ResearchGate, LitCovid, DBPia, and RISS, of which a total of 42 papers were selected in the final stage based on 2013 to 2022 using PRISMA flow diagram. Results: This study suggested to indicate the changes in the cosmetics market due to the emergence of cosmetics curation services after the coronavirus disease‐19 pandemic, advanced changes in consumer purchase patterns following the 4th Industrial Revolution, and significant future prospects of cosmetics curation services. Conclusion: As the beauty and cosmetology industry is expected to develop in the future, it will grow as a centerpiece of the beauty industry and symbolizes nationalized cultural pride. Therefore, this review article will be continuing to promote customization as a premium beauty service for dermatological condition in Republic of Korea through corporate analysis. [ABSTRACT FROM AUTHOR]

Background: In 2019, coronavirus disease‐19 (COVID‐19) continues, and it is evolving and starting again. It is a situation to keep in mind that now is the era of With Corona (WC) and Long‐COVID. "WC" will be a transformation of the quarantine system. The current situation is associated with health and beauty. Sustainability of healthy beauty is giving new meaning to well‐being and well‐dying. Objectives: Therefore, in this study, we empirically analyzed the changes in the perception of health and beauty among cosmetic consumers in the metaverse, which are recently becoming an issue in the WC era. Methods: It was created by searching keywords such as "With Corona," "Health," "Life Beauty," "Customized inner beauty," "Customized cosmetics," "Metaverse," "DTC GT," etc. This study was conducted with reference to PubMed, Google Scholar, Riss, Scopus, and ResearchGate. Accordingly, a total of 472 papers were researched, and among them, 32 papers, which are the focus of the study, were finally included in this study. Results: As the era of WC changes, a new paradigm of converting the customer experience of the beauty market into a metaverse will be beginning. Accordingly, it is necessary to pay attention to changes in the cosmetic industry by reflecting the needs of consumers. Conclusion: It is necessary to create a new mobile platform that encompasses three‐dimensional health and beauty life using direct‐to‐customer genetic testing (DTC GT) with Web 3.0 in the metaverse that integrates life health and beauty in the WC era. Accordingly, it is expected that this article will be used as an invaluable marketing material in preparation for new changes in the metaverse cosmetics market in the future by clearly understanding the needs of consumers in the cosmetics industry, which are changing as they transformation to WC era. [ABSTRACT FROM AUTHOR]

Introduction: There is limited basic research on carbon dioxide (CO2) fractional laser, indicating blind spots in CO2 fractional laser treatment of certain diseases. This study aimed to organize previous literature, summarize the current research, and speculate on possible future development. Methods: We searched document data on fractional CO2 lasers from the Web of Science core collection database and retrieved 928 articles from 2004 to 2021. CiteSpace software was used to analyze the main institutions, authors, subject hotspots, and research frontiers in global CO2 fractional laser research. Results: The results revealed that 928 related papers were published in the past 18 years (2004–2021), and the number has increased annually. The publications were written by 3239 authors from 626 institutions in 60 countries/regions. The United States (US) dominates this field (312 documents), followed by Italy (289), and South Korea (88). Lasers in Surgery and Medicine is the journal with the most publications and citations, and Uebelhoer is the central author. The main research hotspots include vulvovaginal atrophy, fractional photothermolysis, keloids, drug delivery, gene expressions, facial acne scarring, resurfacing, vitiligo, and photo damage. Conclusion: Using CiteSpace, this paper draws a map of authors, institutions, and keywords in fractional CO2 laser from 2004 to 2021; summarizes the main authors, institutions, research hotspots, and cutting‐edge topics of global fractional CO2 laser technology in recent years; and summarizes the current application status of global fractional CO2 laser in disease treatment. It also provides new ideas for the future application and research of fractional CO2 lasers. [ABSTRACT FROM AUTHOR]

Aims: The purpose of this paper was to review the literature focusing on the scalp health of the Korean people in the COVID‐19 blue era and the possibility of significant development as an academic. Methods: This review paper is a literature review, and the method is a narrative review. Results: It was found that the higher the awareness of hair loss, the better the scalp and hair management behavior. South Korea needs to develop systematic customized management methods, scalp programs, and products due to the development of the COVID‐19 era and the development of the 4th industry. Conclusion: South Korea still needs to improve the expertise of tricolologists and national social security insurance and research along with the growth of the beauty and healthcare service industry in the COVID‐19 blue era. [ABSTRACT FROM AUTHOR]

Background: Problematic toenails caused by various diseases that are infected by various bacteria are discolored or deformed if left unattended for a long time are gradually increasing in modern society. Accordingly, the present study examines the anti‐bacterial effects of LCN products, focused on Pseudomonas aeruginosa and Trichophyton rubrum, which can appear in problematic toenail symptoms. After the treatment, a significant anti‐bacterial effect occurring on problematic toenails when a product containing silver ion (Ag+) will be analyzed. Methods: The anti‐bacterial activity of LCN functional gel products in anti‐fungal and/or anti‐bacterial potency was confirmed by the paper disk method against two strains (Pseudomonas aeruginosa and Trichophyton rubum). Results: From July 2019 to October 2019, 30 men and women in their 20s and 50s who needed to manage problematic toenails in Wonju city, Gangwon‐do, Republic of Korea, were asked to use LCN products once every two weeks. After 4 months, changes in the managed toenails were observed. Both products showed very good anti‐microbial activity against, Trichophyton rubum but a very weak one against Pseudomonas aeruginosa. Conclusion: As a result of this study, although there was a difference between individuals, the feet treated with LCN products showed effective anti‐bacterial activity against topical anti‐bacterial effects. [ABSTRACT FROM AUTHOR]

Background: The beauty industry, one of the face‐to‐face the essential industries in the COVID‐19 pandemic, has been hit hard. Aims: We present the current state of the beauty ecosystem in the corona pandemic and the future direction of the beauty industry after COVID‐19. Methods: This review paper is a literature review, and a descriptive review approach was used in this study. A total of 100–150 references were selected using representative journal search sites such as PubMed, Google Scholar, Scopers, Research Gate, and RISS, and a total of 24 papers were finally selected as of 2017–2022 using PRISMA flow diagram. Results: In Korea, the beauty industry, which is essential to face‐to‐face due to COVID‐19, was hit hard. The contraction of consumer sentiment led to a drop in sales. The online market has become more active as offline activities have declined sharply. Even during the COVID‐19 era, the Republic of Korea is an IT powerhouse. With the widespread use of K‐drama and K‐pop, the interest in Korean beauty and fashion has increased rapidly throughout the world. Therefore, K‐Makeup, hair, skincare, and nailcare are all the rage through YouTube. Predict new changes in the Korean beauty industry market, which is the center of K‐beauty and K‐cosmetics. As a leader in the beauty industry, the Republic of Korea will present the sustainability of the beauty ecosystem and the direction of its development. [ABSTRACT FROM AUTHOR]

Background: This paper describes the background research and validation related to the formulation of a novel antioxidant product. Two defined outcomes were sought. Firstly, a combined efficacy of antioxidant ingredients in quenching free oxygen radicals. Secondly, the investigation into whether a vitamin C derivative sodium salt was elastin conserving in contrast to current vitamin C/l‐ascorbic acid variations that have been reported to negatively affect elastin constitution and regeneration. Materials and Methods: A leading l‐ascorbic acid antioxidant available on the market was compared with the experimental new product in two studies. In the first experiment, the products were compared to assess their antioxidant properties. The evaluated products TOPICAL ANTIOXIDANT 1 and TOPICAL ANTIOXIDANT 2 were applied to human skin cultures (25–30 mg/cm2) for a total of 72 h of treatment and exposed to oxidative stress. The generation of free radicals was semi‐quantitatively assessed by measuring the fluorescence intensity of the deacetylation and oxidation of the probe dichlorofluorescein diacetate (DCFH‐DA). In the second experiment, an ex vivo skin model (derived from patients undergoing facelift procedures) was used to assess elastin preservation. Three skin explants were topically subjected to the two formulations daily for 7 days. The skin was then prepared and fixed for immunofluorescent assessment after staining with CD44 and tropoelastin antibodies. Images were then analyzed using ImageJ. Results: A full description of the different components selected for the new formulation is presented. In the first study, the experimental formulation performed with absolute equivalence to the comparator in its radical quenching capacity; both showed extremely effective antioxidant function. In the second study, the comparator negatively affected the existing elastin with areas of breakdown and diminished staining. In contrast, the new formulation showed good conservation of healthy elastin in all sections demonstrating elastin preservation. Conclusion: A new antioxidant formulation was carefully designed with multiple actives that show an equivalent antioxidant capacity to a leading product on the market. More importantly, the vitamin C component shows direct elastin conservation and improvement as opposed to the comparator, which had negative effects on elastin preservation. This is in keeping with little‐known literature reports on vitamin C and its negative effects on elastin and validates the use of a sodium salt derivative, which appears to have protective effects on elastin. These findings support the overall regenerative extracellular matrix changes seen with TriHex® technology in other products. [ABSTRACT FROM AUTHOR]

Background: As the world's population of people vaccinated with the COVID‐19 vaccine increases, adverse reactions are increasingly being reported. There have been progressive reports of the effects of COVID‐19 vaccination on cosmetic fillers or prostheses, but they have not been reviewed based on their clinical morphologic patterns. This article reviewed the progress of research on adverse reactions to cosmetic implants after COVID‐19 vaccination. Methods: We researched the English‐language literature up to October 15, 2022, using predefined keywords to identify relevant studies about adverse reactions to cosmetic implants after the COVID‐19 vaccination, collecting patient characteristics, implant type, the time interval between vaccination and implantation or injection, time of onset, symptoms, treatments, and outcomes. Results: Among the adverse reactions to implants associated with COVID‐19 vaccination, we distinguished between (1) injectable fillers and (2) surgical prosthetic implants. The most common adverse reactions were at the site of hyaluronic acid injection and breast prosthesis after Pfizer vaccination, mainly DIRs, and mainly manifested as edema, rash, fever, and capsular contracture. This paper also reported the possible causes, treatments of DIRs, and limitations of current studies. Conclusions: In this article, we attempted to investigate and discuss all the adverse reactions of cosmetic implants related to COVID‐19 vaccination in the current literature, to unmask these reactions and make a more accurate assessment of vaccine safety. [ABSTRACT FROM AUTHOR]

Background: New changes are taking place in the beauty and cosmetology market due to changes in daily life due to coronavirus disease‐19 (COVID‐19) and environmental alteration caused by the spread of live commerce. Purpose: This study technically investigated the future value and direction of vegan cosmetics from food to cosmetics by focusing on good ingredients after COVID‐19 pandemic and changing the needs of consumers in the beauty and cosmetics industry. Methods: This review paper is a critical literature review, and a narrative review approach has been used for this study. A total of 300–400 references were selected using representative journal search websites such as PubMed, Google Scholar, Scopus, RISS, and ResearchGate, which a total of 45 papers were selected in the final stage based on 2009 to 2022. Result: As environmental problems increased after the COVID‐19 pandemic, we tried to understand the needs of consumers for vegan cosmetics, which are good ingredients and good cosmetics. Therefore, this narrative review clearly shows the need for beauty and cosmetics industry consumers to pursue good consumption due to the global COVID‐19 pandemic. Conclusion: Accordingly, this literature review will need to identify consumer needs for vegan cosmetics that started from vegan foods and develop the applications for the development of customized inner beauty products, customized vegan inner beauty products and/or customized vegan cosmetics using customized cosmetics. This is expected to be used as important marketing materials for the global vegan cosmetics market that confirms new changes in the cosmetics market. [ABSTRACT FROM AUTHOR]

Background: Stratum corneum is located in the outermost layer of the skin and is the most important part of the skin barrier. Stratum corneum mainly contains keratinocytes, lipids, and desmosomes. Their normal metabolic process is closely related to the function of skin barrier. Aims: This paper reviews the structure and function of stratum corneum, influencing factors, skin diseases, and common solutions. Methods: An extensive literature search was conducted on the structure and function of stratum corneum, influencing factors, skin diseases, and common solutions. Results: This paper reviews the structure and function of stratum corneum and the influence of various factors on stratum corneum metabolism. At the same time, the existing skin problems, skin diseases, and common solutions are summarized. Conclusions: This information will help to understand the function, molecular mechanism, and influencing factors of stratum corneum metabolism, and provide new ideas for stratum corneum health management and cosmetic research and development. [ABSTRACT FROM AUTHOR]

Background: The ongoing pandemic of coronavirus disease 2019 (COVID‐19) is putting millions at risk in more and more countries, making it a serious public health threat worldwide. Under such circumstances, "Untact" and "Streaming Life" are emerging as major trends in the recent service industry, and the beauty lives commerce market is expanding centering on mobile shopping in Republic of Korea. Objectives: This study descriptively investigated changes in the needs of beauty and cosmetics industry consumers for good consumption of the MZ generation after COVID‐19 pandemic. Methods: This review paper is a literature review, and a narrative review approach has been used for this study. A total of 300 to 400 references were selected using representative journal search websites such as PubMed, Google Scholar, Scopus, ResearchGate, and RISS, of which a total of 39 papers were selected in the final stage based on 2009 to 2021. Results: An E‐commerce packaging production and use have grown steadily in recent years as online purchases increase. As a result, the impact on the environment has also increased. Humanity faces climate change, pollution, environmental degradation, and/or destruction of air, soil, water, and ecosystems. The climate and environmental crisis will be one of the greatest challenges in human history. This review paper conducted a comprehensive study on the good consumption of MZ generation for K‐Cosmetics in COVID‐19 pandemic. Conclusion: This review clearly identifies the needs of consumers in the beauty and cosmetics industry for good consumption of the MZ generation for K‐beauty in COVID‐19 pandemic. In addition, it is expected to be used as an important marketing material in the global cosmetics market by confirming new changes in the Korean cosmetic market, which is the center of K‐Beauty and K‐Cosmetics. [ABSTRACT FROM AUTHOR]

Background: According to recent experience, people are willing to wear masks to protect themselves from environmental issues such as infections, allergies, and fine dust such as SARS in 2003, swine flu A (H1N1) in 2009, and COVID‐19 in 2019. Objectives: The objective of this study was to investigate the changing conditions of cosmetics use worldwide due to the increase in mask usage. Methods: This review paper is a literature review, and a narrative review approach has been used for this study. A total of 300–400 references were selected using representative journal search websites such as PubMed, Google Scholar, Scopus, and RISS, of which a total of 39 papers were selected in the final stage based on 2006–2021. Results: Masks must be worn due to environmental issues and/or infectious diseases, for example, COVID‐19. Skin troubles were dramatically increased by the increased use of masks. Additionally, research‐related natural products for skin soothing ingredients and makeup products were suggested. Conclusion: This review is expected to be used as an important marketing material for new changes in the cosmetics market by clearly grasping the needs of consumers in the beauty and cosmetics industry from the viewpoint of using masks after COVID‐19. [ABSTRACT FROM AUTHOR]

Background: Although the negative impacts of idiopathic hirsutism (IH) on psychological aspects are well‐documented, there is no enough study estimating the prevalence of this endocrine disorder. Objective: This meta‐analysis was conducted to estimate the pooled prevalence of IH in the women population. Methods: PubMed, Scopus, and Web of Science databases were explored to obtain papers published from inception to September 2020 investigating the prevalence of IH in women. A meta‐regression was conducted to assess the impact of polycystic ovary syndrome (PCOS) diagnostic criteria, and ethnicity on the pooled prevalence of IH. Results: Of 8346 records retrieved through searching databases and other sources, eight studies were selected for the final analyses. The pooled prevalence of idiopathic hirsutism among women, regardless of PCOS diagnostic criteria, and the race was 7.74% (95% CI: 4.10, 14.14). The meta‐regression analysis showed that the pooled prevalence of idiopathic hirsutism did not significantly differ based on the PCOS diagnostic criteria and ethnicity. A subgroup analysis based on the PCOS criteria showed the pooled prevalence of 7.24% (95% CI: 2.84, 17.24), 13.05% (95% CI: 10.02, 16.81), and 3.12% (95% CI: 2.16, 4.48) for NIH (National Institutes of Health), Rotterdam, and not reported PCOS diagnostic criteria groups, respectively. The subgroup analysis based on the ethnicity estimated a pooled prevalence of 6.01% (95% CI: 1.87, 17.69) and 9.36% (4.07, 16.63) for European and Asian groups, respectively. Conclusion: The meta‐analysis demonstrated that the pooled prevalence of IH was 7.74% and there was no difference between PCOS criteria and ethnicity subgroups. [ABSTRACT FROM AUTHOR]

The pivotal role of the bride's mothers in wedding celebrations is an effective motivation to seek cosmetic therapies, making them frequent patients in a dermatologists' offices. Addressing their aesthetic concerns contributes to their holistic well‐being, but faces an intricate relationship between time availability, financial factors, and the critical emotional context. This article underscores the varying behavioral patterns of mothers of brides when seeking aesthetic treatments, providing tailored strategies for effective communication and decision‐making, based on individual personalities. Additionally, this paper presents a specific timeline for the implementation of these interventions, including neuromodulators, collagen stimulators, and fillers. Understanding the unique traits and expectations of this particular population can lead to improved patient satisfaction, enhanced outcomes, and an overall positive experience. [ABSTRACT FROM AUTHOR]

Background: The popularity of social media appears to be increasing the acceptance of cosmetic treatments, prompting more consumers to seek cosmetic treatments. As the estimated prevalence of acne vulgaris among adult women may be as high as 54%, acne is commonly observed among patients presenting for cosmetic treatments. Concomitant treatment of acne in the aesthetic patient population will improve overall clinical outcomes. Aims: The goal of this work was to deliver a high‐quality ethical and evidence‐based educational program to physicians and adjunctive health care providers to advance patient care. Methods: This paper is based on a webcam presentation with roundtable discussion by several notable experts in their field. Results: A range of topical medications, injectable products, chemical peels, and energy‐based devices are available for treating acne vulgaris. In most instances, these are compatible with rejuvenation procedures in the aesthetic patient. Conclusion: The growth of social media is raising awareness of aesthetic procedures and appears to be increasing the number of patients seeking aesthetic treatment. Educating patients about the importance of treating acne vulgaris can improve overall treatment outcomes. In most instances, the presence of acne is not a barrier to aesthetic care. [ABSTRACT FROM AUTHOR]

Introduction: The proliferation of providers and practitioners of cosmetic botulinum toxin and dermal filler has profound public health implications. The Advertising Standards Authority (ASA) regulates the use of advertising materials in the United Kingdom and prohibits the promotion of prescription‐only medicines. Aims: We aim to perform a cross‐sectional analysis of the practitioners in London, UK to evaluate the distribution of clinics within Greater London, prices advertised for interventions, and compliance with the ASA code. We also aim to identify whether there are any differences in cost of botulinum toxin or dermal filler between the boroughs. Methods: Between December 2021 and January 2022, we performed a systematic search using the internet search engine Google. Five searches were performed (1) [london] botox, (2) [london] botulinum toxin, (3) [london] anti wrinkle injection, (4) [london] filler, (5) [london] dermal filler. One hundred websites per search string were systematically reviewed and those which met the inclusion/exclusion criteria of each search string were included and analyzed. Each clinic's product/service range compliance with the ASA/CAP code was assessed. Any reference to Botulinum Toxin or anti‐wrinkle injections was noted and analyzed. Further analysis would look to calculate price per milliliter (mL) of botulinum toxin and dermal filler per borough and to calculate whether there were any statistical differences between the 32 different London boroughs. Results: A total of 500 websites were visited and evaluated. After removal of duplicates, a total of 233 independent clinics was identified. A total of 206 out of the 233 clinics sampled (88%) were in direct infringement of the enforcement notice through advertising a prescription medicine. The overall average cost per mL of dermal filler was £330.89 and there was a statistically significant variance across London boroughs (p < 0.05). The overall average cost per mL of Botulinum Toxin was £284.45 and the variance across London boroughs was close to significant (p = 0.058). Conclusion: This paper demonstrates poor compliance with the ASA/CAP guidelines and further provides an insight into the industry mechanics associated with aesthetic injectables in a major UK city, identifying regional variance in price and clinic density. The advertising of prescription‐only medication may pose a potential risk to patients and will be an important consideration in proposed legislation to introduce licensing to the industry. [ABSTRACT FROM AUTHOR]

Background: Deep‐learning object detection has been applied in various industries, including healthcare, to address hair loss. Methods: In this paper, YOLOv5 object detection algorithm was used to detect hair follicles in a small and specific image dataset collected using a specialized camera on the scalp of individuals with different ages, regions, and genders. The performance of YOLOv5 was compared with other popular object detection models. Results: YOLOv5 performed well in the detection of hair follicles, and the follicles were classified into five classes based on the number of hairs and the type of hair contained. In single‐class object detection experiments, a smaller batch size and the smallest YOLOv5s model achieved the best results, with an map of 0.8151. In multiclass object detection experiments, the larger YOLOv5l model was able to achieve the best results, and batch size affected the result of model training. Conclusion: YOLOv5 is a promising algorithm for detecting hair follicles in a small and specific image dataset, and its performance is comparable to other popular object detection models. However, the challenges of small‐scale data and sample imbalance need to be addressed to improve the performance of target detection algorithms. [ABSTRACT FROM AUTHOR]

Background: For decades, the notion that elective surgeries and cutaneous procedures should be postponed for 6–12 months in patients on, or recently administered with isotretinoin, has been widely accepted. However, some recent studies showed the need for a change in this regard. Method: Here, we reviewed the existing data in this regard through searching on PubMed, Google Scholar, and Scopus. All of the relevant papers published in English, until October, 2022, which we could access to their full‐texts, were included. Results: We found some recommendations made by plastic surgeons, dermatologists, ENT surgeons, ophthalmologists, orthopedic surgeons, and dentists regarding the correct timing of procedural interventions in patients on, or recently administered with isotretinoin and tried to summarize them to provide a practical guide for clinicians. Conclusion: Physicians may discuss with patients regarding the known risk of abnormal wound healing in the setting of systemic isotretinoin treatment and suggest that, when possible, surgical procedures be postponed until the activity of the retinoids has time to subside. It is even more important regarding patients with darker skin phototypes to follow an even more strict guideline. [ABSTRACT FROM AUTHOR]

Objective: Facial aging is a complex process that involves genetic, biological, and environmental factors. This paper aimed to present the first aesthetic and safety outcomes of a hybrid filler that combines hyaluronic acid (HA) (20 mg/mL) and calcium hydroxyapatite (HA/CaHa). Methods: Prospective and non‐randomized interventional study conducted on consecutive healthy patients who attended the clinic for an aesthetic facial rejuvenation procedure. HA/CaHa was injected with 23G cannula (retrograde threads, 1.25 mL per side) in the preauricular region. Ultrasound examinations, elastography images, and 2D and 3D photographs were performed before and after treatment. The primary endpoint were the volumetric changes at Day 180. Results: Fifteen patients were included in the study. At Day 180 after treatment, median (interquartile‐range) volume increased by 2.1 (1.9–2.3) cc and 2.1 (1.8–2.2) cc in the right‐ and left‐side, respectively, p < 0.0001 each. As compared to pretreatment values, facial‐tension vectors significantly increased by 2.2 (1.6–2.2) mm and 2.0 (1.7–2.2) mm in the right and left side, respectively, p < 0.0001 each. Elastography images demonstrated an increase in collagen fibers at post‐treatment Day 60, which was confirmed on Day 90, and reached the peak effect between Days 90 and 180. Regarding safety, there were no either unexpected or serious treatment‐related adverse events. Most patients experienced a mild redness and inflammation that resolved within the first 48 h without treatment. Conclusions: The HA/CaHa hybrid filler (HArmonyCa™), besides its volumizing and lifting properties, was associated with an increase in the viscoelasticity, both at the level of the reticular dermis and the subcutaneous cellular tissue, which might be indicative of the formation of new collagen fibers. [ABSTRACT FROM AUTHOR]

Background: Compound glycyrrhizin has achieved outstanding results in the treatment of various skin diseases. However, the use of mesotherapy to inject compound glycyrrhizin into the skin to treat acne is still understudied. Aims: This paper aims to explore the effects of mesotherapy introduction of compound glycyrrhizin injection on the acne. Materials & Methods: A total of 108 patients were included in this study and divided into the control group (n = 54) and the observation group (n = 54). The control group was treated with topical clindamycin gel, while the study group was treated with topical clindamycin gel + mesotherapy and compound glycyrrhizin injection. Skin transepidermal water loss (TEWL), cuticle water content, acne severity, adverse reactions, and inflammatory reactions were documented before and after treatment in the two groups. Results: The usage of mesotherapy to inject compound glycyrrhizin into the skin of acne patients more effectively treat acne than traditional clindamycin gel. The mesotherapy compound glycyrrhizin can more effectively protect the skin barrier of patients and reduce the loss of skin moisture. Compared with the traditional clindamycin gel, the combination of mesotherapy and compound glycyrrhizin more effectively inhibit the inflammatory reaction in acne patients and reduce skin damage in acne patients. Discussion/Conclusion: Mesoderm introduction of compound glycyrrhizin injection has better effects on the treatment of moderate to severe acne than clindamycin gel. [ABSTRACT FROM AUTHOR]

Objective: Nonsurgical rhinoplasty has become increasingly popular among patients who want to improve the aesthetic aspects of their nose and do not accept the risks and/ or cost of surgical rhinoplasty. The main goal of the current paper was to present the preliminary aesthetic and clinical outcomes of an innovative injection technique for nose sculpturing with hyaluronic acid (HA) filler. Methods: Retrospective analysis of a prospective clinical registry of patients who attended one of the study centers and were candidates for non‐surgical nose reshaping between October 2019 and November 2020. A 25 mg/mL HA filler was administered, in all the cases, by using a syringe with a fixed microneedle (30G/8mm). All patients were injected at three key nose points with the following order: (1) Tip (maximum HA injected 0.2 mL); (2) columella (maximum HA injected 0.3 mL); and (3) Radix and Dorsum (maximum HA injected 0.3 mL). Degree of patient satisfaction with the treatment was assessed by using a five‐points Likert scale. The primary endpoint was the degree of patients' satisfaction 12 months after treatment. Results: One‐hundred‐and‐one patients (91 women) were included in the study. Fifty‐six (56%) patients underwent a unique treatment‐session and 44 (44%) subjects needed an additional touch‐up. Eighty‐five (84.2%) patients were very satisfied with the treatment results. Six (5.9%) patients reported moderate adverse events, which were successfully controlled with medical therapy. Conclusions: Our nose sculpturing technique, by using hyaluronic acid filler, was an effective, predictable, and relatively safe procedure, that obtained a high degree of patient satisfaction. [ABSTRACT FROM AUTHOR]

Background: The search for ever more lasting and safe aesthetic modalities is a constant. For this reason, biostimulation is finding more and more space in clinics; relatively simple, effective, and safe procedures, a procedure that delivers what it promises. Biostimulation is nothing more than an increase in collagen production, primarily type I, with the aim of facial or body rejuvenation. Aims: Evaluated some years ago as remarkable antimicrobial therapy, today it gains notoriety for its versatility in other areas, one of which is biostimulation, which has been growing. This paper aims to report a case of biostimulation through ozone therapy, as well as the protocol used, its indications, and contraindications. Patients/Methods: A case report of rejuvenation with ozone therapy and a literature review. Results: Among biostimulatory treatments available, one has been gaining space among professionals and scientific recognition, ozone therapy. Conclusion: It is a promising aesthetic therapeutic modality with efficient and safe results and high patient compliance and satisfaction. [ABSTRACT FROM AUTHOR]

Background: Acne vulgaris, a chronic inflammatory dermatosis, affects approximately 85% of adolescents and young adults.The level of vitamin D in acne patients and the effect on acne patients of a vitamin D supplementation have previously been documented; however, it remains to be disputed whether vitamin D deficiency is normal in acne patients. Aims: This paper explores the relationship between vitamin D and acne levels and the advantageous implications of vitamin D supplements on acne. Methods: From every database start date until December 2020, we checked the PubMed, EMBASE, MEDLINE and the Cochrane libraries. Case‐controls or randomized controlled trial reporting on the serum 25(OH)D level and the efficacy of vitamin D supplement to acne patients were included. Results: The serum 25(OH)D levels in acne patients is lower (standardized mean difference = −7.66 ng/ml; 95% confidence interval (CI) = −10.92 to −4.40). Articles also revealed the prospect of a therapeutic breakthrough through the supplementing of vitamin D for acne patients. Conclusion: Our research offers a new guide in the field of acne prevention and health care. [ABSTRACT FROM AUTHOR]

Background: With online purchases' skyrocketing due to COVID‐19, there has been a big change in the beauty products consumers' purchase. Aims: The purpose of this paper was to review the literature focusing on changes in purchasing patterns in the beauty market after COVID‐19 pandemic. Methods: This review paper is a literature review, and the method is a narrative review. Results: The past and present purchasing of beauty products were rapidly changed. The cosmetics and many beauty products were increased purchasing rate due to marketing of Wanghong broadcasting. Also, the non–face‐to‐face market environment has expanded after COVID‐19. Conclusion: As COVID‐19 pandemic changes consumer values and lifestyle, its role and function are changing and its purchasing patterns are altered. [ABSTRACT FROM AUTHOR]