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Four mononuclear complexes of Cu(II) and Zn(II) having a Schiff-base ligand and 1,10-phenanthroline/2,2′-bipyridine have been synthesized and characterized. From electronic spectral and magnetic susceptibility data, octahedral geometry has been proposed for the complexes. DNA-binding behaviors of these complexes are studied by absorption titration, electrochemical, and viscosity methods. The results indicate that the complexes bind to calf thymus DNA in an intercalative mode. The gel electrophoresis results reveal that 1 cleaves pBR322 DNA effectively. The ligand and its complexes have been screened for their antimicrobial activities against a few microorganisms. The data exhibit that they are better antimicrobial agents than the ligand. [ABSTRACT FROM PUBLISHER]

A new series of acyclic mononuclear copper(II) complexes have been prepared by Schiff-base condensation derived from 5-methylsalicylaldehyde, diethylenetriamine, tris(2-aminoethyl) amine, triethylenetetramine, N,N-bis(3-aminopropyl)ethylene diamine, N,N-bis(aminopropyl) piperazine, and copper perchlorate. All the complexes were characterized by elemental and spectral analyses. Electronic spectra of the complexes show a d-d transition in the range 500-800 nm, electrochemical studies of the complexes show irreversible one-electron-reduction process around -1.10 to -1.60 V. The reduction potential of the mononuclear copper(II) complexes shifts toward anodic direction upon increasing the chain length of the imine compartment. ESR spectra of the mononuclear copper(II) complexes show four lines, characteristic of square-planar geometry, with nuclear hyperfine spin 3/2. The copper(II) complexes show a normal room temperature magnetic moment value μeff = 1.72-1.76 BM, close to the spin-only value of 1.73 BM. Electrochemical and catalytic studies of the complexes were compared on the basis of increasing the chain length of the imine compartment. All the complexes were screened for antifungal and antibacterial activities. [ABSTRACT FROM AUTHOR]