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Off-site construction (OSC) is an environmentally friendly building method with substantial benefits, yet it encounters challenges, particularly in supply chain efficiency. Current research on off-site construction supply chain (OSCSC) challenges faces issues such as dispersion, cross-disciplinarity, and timeliness. This is despite a number of studies in recent years focusing on the optimization of OSCSC to improve their performance and efficiency. However, the current literature still lacks a comprehensive summary of OSCSC problems, which hinders the popularization of OSC. To address this, improve OSCSC efficiency, and enhance OSC practicability, this paper conducted a thorough review of 244 published articles. Utilizing bibliometrics and scientometrics methods, it identified research trends, prominent researchers, and topics. Current OSCSC issues were further extracted and classified from the internal supply chain perspective. The findings reveal key issues hindering OSCSC efficiency, offering practitioners, policymakers, and researchers a nuanced understanding of current research issues. In addition, this paper provides future research directions and performance optimization recommendations, contributing to solving OSCSC challenges and exploring innovative solutions for continuous improvement in the OSCSC field. [ABSTRACT FROM AUTHOR]