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Start Over Author "Umemura T." Journal journal of comparative pathology
25 results on '"Umemura T."'

21. An immunohistochemical study on the@?@?tissuespecific localization of metallothionein in dogs

Author

Shimada, A., Yanagida, M., and Umemura, T.

Abstract

To study the tissue specificity of metallothionein (MT) expression, tissues of dogs ranging in age from 1 day to 18 years were examined immunohistochemically. Of the organs examined, liver and kidney showed the strongest immunoreactivity; a comparable intensity of MT immunolabelling was noted in the two organs in adult animals. In the central nervous system, astrocytes and ependymal cells showed MT immunoreactivity. MT labelling was shown in the sustentacular cells of the olfactory epithelium, but immunoreactivity was slight in the epithelium of the respiratory tract. Slight MT immunoreactivity was demonstrated in the epithelium of a variety of glands (sweat, uterine, mammary, olfactory, perianal and thyroid) and in parietal cells of the fundic glands of the stomach. Sporadic MT immunolabelling was demonstrated in the columnar and goblet cells of the small and large intestines, surface mucosal cells of the stomach and epithelial cells of the hair follicles. These findings may help in understanding important features of MT, such as its dynamic induction mechanism, its systemic degradation pathway and the possible biological functions.

Published
1997
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22. Non-functional pituitary chromophobe adenoma in a calf

Author

Shimada, A., Hara, K., Umemura, T., Kagota, K., Yamaga, Y., Ozaki, K., and Narama, I.

Abstract

A 5-month-old male calf showed neurological signs, including circling, inco-ordination, depression, blindness and eventual recumbency. On necropsy, a mass measuring 3.5x4x5x5 cm was found at the base of the brain, at the level of the pituitary gland. The hypothalamus and optic nerves were compressed by the dorsally expanding mass. Non-functional pituitary chromophobe adenoma was diagnosed from histochemical, immunohistochemical phobe adenoma was diagnosed from histochemical, immunohistochemical and electron microscopical findings.

Published
1996
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25. An immunohistochemical study on the tissue-specific localization of metallothionein in dogs.

Author

Shimada A, Yanagida M, and Umemura T

Subjects
Animals, Central Nervous System chemistry, Digestive System chemistry, Dogs, Female, Immunohistochemistry, Kidney chemistry, Liver chemistry, Male, Metallothionein immunology, Respiratory System chemistry, Skin chemistry, Tissue Distribution, Metallothionein chemistry
Abstract

To study the tissue specificity of metallothionein (MT) expression, tissues of dogs ranging in age from 1 day to 18 years were examined immunohistochemically. Of the organs examined, liver and kidney showed the strongest immunoreactivity; a comparable intensity of MT immunolabelling was noted in the two organs in adult animals. In the central nervous system, astrocytes and ependymal cells showed MT immunoreactivity. MT labelling was shown in the sustentacular cells of the olfactory epithelium, but immunoreactivity was slight in the epithelium of the respiratory tract. Slight MT immunoreactivity was demonstrated in the epithelium of a variety of glands (sweat, uterine, mammary, olfactory, perianal and thyroid) and in parietal cells of the fundic glands of the stomach. Sporadic MT immunolabelling was demonstrated in the columnar and goblet cells of the small and large intestines, surface mucosal cells of the stomach and epithelial cells of the hair follicles. These findings may help in understanding important features of MT, such as its dynamic induction mechanism, its systemic degradation pathway and the possible biological functions.

Published
1997
Full Text
View/download PDF

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