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Your search keyword '"Bruno, Benedetto"' showing total 7 results
Start Over Author "Bruno, Benedetto" Journal journal of clinical medicine
7 results on '"Bruno, Benedetto"'

2. Relapsed/Refractory Chronic Lymphocytic Leukemia Patients Treated with Fixed Duration Venetoclax-Rituximab: Assessment of Response with Ultrasound, and Relationship with Minimal Residual Disease

Author

Benedetti, Edoardo, primary, Baratè, Claudia, additional, Mavilia, Fabrizio, additional, Bramanti, Emilia, additional, Morganti, Riccardo, additional, Guerri, Valentina, additional, Cervetti, Giulia, additional, Capochiani, Enrico, additional, Bertaggia, Ilaria, additional, Stella, Salvatore Massimo, additional, Traverso, Ginevra, additional, Bruno, Benedetto, additional, and Galimberti, Sara, additional

Published
2023
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4. Surgery and Prophylaxis with Susoctocog-Alfa in Acquired Hemophilia: Case Series and Literature Review.

Author

Sella, Carola, Bardetta, Marco, Valeri, Federica, Dainese, Cristina, Valpreda, Alessandra, Massaia, Massimo, Grimaldi, Daniele, Porreca, Annamaria, Bruno, Benedetto, and Borchiellini, Alessandra

Subjects
LITERATURE reviews, BLOOD coagulation factor VIII antibodies, HEMOPHILIA, BLOOD coagulation factor VIII, PREVENTIVE medicine, CIRCOVIRUS diseases
Abstract

Background: Acquired hemophilia A (AHA) is a rare bleeding disease due to autoantibodies directed against clotting factor VIII (FVIII). Treatment of AHA consists of inhibitor eradication with immunosuppressive therapy (IST) and prompt control of bleeding obtained with bypassing agents or recombinant porcine FVIII (rpFVIII). The latter has recently been licensed for management of acute bleeding in AHA. Unlike treatment with bypassing agents, rpFVIII can be monitored to provide a successful hemostatic effect and avoid overtreatment. Correlation between rpFVIII inhibitor titers and efficacy of rpFVIII treatment remains a matter of debate. Methods: We report three cases of AHA in which rpFVIII was successfully used with an unconventional schedule despite the presence of medium–high titers of the rpFVIII. The modified Nijmegen–Bethesda inhibitor assay (NBA) was used to dose porcine FVIII inhibitors. Result: The presence of rpFVIII inhibitors prior to the exposition to susoctocog-alfa, that may suggest a cross-reactivity with human FVIII inhibitors, did not affect hemostasis. Conclusion: In our experience, rpFVIII demonstrates safety and efficacy in the presence of rpFVIII inhibitors and using an unconventional schedule in both the perioperative and outpatient settings. Laboratory measurement of inhibitors against rpFVIII during treatment is described for the first time. [ABSTRACT FROM AUTHOR]

Published
2023
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5. A Prospective Cross-Sectional Study on the Comparison of Ultrasound Assessment vs. Palpation in Chronic Lymphocytic Leukemia Patients in the Era of Targeted Therapy

Author

Benedetti, Edoardo, primary, Mavilia, Fabrizio, additional, Baratè, Claudia, additional, Bramanti, Emilia, additional, Morganti, Riccardo, additional, Cervetti, Giulia, additional, Capochiani, Enrico, additional, Bruno, Benedetto, additional, Pelosini, Matteo, additional, Stella, Salvatore Massimo, additional, and Galimberti, Sara, additional

Published
2022
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6. Early Diagnosis of Neutropenic Enterocolitis by Bedside Ultrasound in Hematological Malignancies: A Prospective Study

Author

Benedetti, Edoardo, primary, Bruno, Benedetto, additional, Martini, Francesca, additional, Morganti, Riccardo, additional, Bramanti, Emilia, additional, Caracciolo, Francesco, additional, Galimberti, Sara, additional, Lippolis, Piero, additional, Neri, Emanuele, additional, Arena, Chiara, additional, Cerri, Francesca, additional, Ricchiuto, Vittorio, additional, Pelosini, Matteo, additional, Orciuolo, Enrico, additional, and Petrini, Mario, additional

Published
2021
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7. Organ Stiffness in the Work-Up of Myelofibrosis and Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Author

Benedetti, Edoardo, primary, Tavarozzi, Rita, additional, Morganti, Riccardo, additional, Bruno, Benedetto, additional, Bramanti, Emilia, additional, Baratè, Claudia, additional, Balducci, Serena, additional, Iovino, Lorenzo, additional, Ricci, Federica, additional, Ricchiuto, Vittorio, additional, Buda, Gabriele, additional, and Galimberti, Sara, additional

Published
2020
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