1. IgG4 subclass antibodies impair antitumor immunity in melanoma
- Author
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Karagiannis, Panagiotis, Gilbert, Amy E., Josephs, Debra H., Ali, Niwa, Dodev, Tihomir, Saul, Louise, Correa, Isabel, Roberts, Luke, Beddowes, Emma, Koers, Alexander, Hobbs, Carl, Ferreira, Silvia, Geh, Jenny L.C., Healy, Ciaran, Harries, Mark, Acland, Katharine M., Blower, Philip J., Mitchell, Tracey, Fear, David J., Spicer, James F., Lacy, Katie E., Nestle, Frank O., and Karagiannis, Sophia N.
- Subjects
Immunity -- Research ,Immunoglobulin G -- Health aspects ,Melanoma -- Research ,Health care industry - Abstract
Host-induced antibodies and their contributions to cancer inflammation are largely unexplored. IgG4 sub-class antibodies are present in IL-10-driven Th2 immune responses in some inflammatory conditions. Since Th2-biased inflammation is a [...]
- Published
- 2013
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