Search

Cirrhotic patients often have an increased cardiac load and impaired myocardial systolic and diastolic functions, which further cause abnormal myocardial structure, and such patients may develop the symptoms of heart failure under stress, which is called cirrhotic cardiomyopathy (CCM). This disease attracts little attention due to its insidious onset. B-type natriuretic peptide (BNP) is secreted by cardiomyocytes and can sensitively reflect the change in ventricular function, and it is widely used in the pathogenesis, treatment, and prognosis of cardiovascular diseases. BNP plays an important role in the diagnosis and treatment of respiratory and renal diseases, and meanwhile, recent studies have shown a significant increase in BNP in cirrhotic patients, which is closely associated with the severity of cirrhotic ascites, varices, and liver dysfunction. BNP can also reveal myocardial injury when there are no obvious symptoms of CCM. This article reviews the expression of BNP and its significance in patients with CCM. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)