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Objective: In this study, we aimed to investigate whether platelet lymphocyte ratio (PLR) and Mean platelet volume (MPV) values can be used as prognostic and diagnostic markers in laryngeal cancer.Methods: A total of 242 patients with laryngeal pathology were reviewed retrospectively. PLR, MPV and platelet values were compared in patients with benign and malignant pathologies. The correlation of PLR, MPV and platelet values of patients with malignant pathologies with their age, gender, smoking, alcohol use, degree of differentiation, and clinical stage was investigated.Results: The PLR values were significantly higher in smokers (p=0.009), alcohol drinkers (p=0.001), clinical stage IV patients (p=0.001), and patients with poor differentiated laryngeal cancer (p=0.001), compared to nonsmokers, non­alcohol consumers, clinical stage III patients, and patients with well-differentiated laryngeal cancer. MPV values were significantly lower in patients with clinical stage IV (p=0.018), and poor differentiated (p=0.010), laryngeal cancer com­pared to patients with clinical stage III and well-differentiated laryngeal cancer. The PLR value was significantly higher in the malignant group than in the benign group (p

Objective: Fecal diversion is often indicated in cases with fecal incontinence, Fournier’s gangrene, anal fistula, and inoperable obstructive anorectal cancer. Trephine colostomy can be performed without necessitating laparotomy. We present our experience related to the outcome of trephine sigmoid colostomy.Methods: The retrospective study included 14 patients who underwent trephine colostomy due to various conditions including Fournier’s gangrene, inoperable anorectal cancer, recto-vaginal fistula, and benign stricture due to radiotherapy at our clinic between January 2010 and January 2015.Results: Patients comprised 4 females and 10 males with a mean age of 52.07 years. The indications for stoma formation were Fournier’s gangrene in 7 cases, inoperable anorectal cancer in 5, rectovaginal fistula in 1, and benign stricture due to radiotherapy in 1 case. Eight patients underwent surgery under regional anesthesia. All the patients underwent trephine loop sigmoid colostomy. One patient had second operation on the postoperative period due to colostomy prolapse. The temporary stomas were closed in 3 months. Mean length of hospital stay was 14 days.Conclusion: Trephine stoma is a relatively simple, safe and rapid procedure and an effective alternative to colostomy formation without laparotomy indications. It can be performed under emergency or elective conditions with low morbidity. J Clin Exp Invest 2015; 6 (2): 87-90Key words: Fecal diversion, trephine stoma, outcomes, Amaç: Saptırıcı stoma sıklıkla fekal inkontinans, Fournier gangreni, anorektal fistüller ve tıkayıcı inoperable anorektal tümörler gibi durumlarda yapılır. Trefin stoma (TS) laparatomi yapılmaksızın yapılabilir. Biz bu çalışmada TS vakalarımızın sonuçlarıyla ilgili deneyimimizi paylaşmayı amaçladık.Yöntemler: Bu çalışma 2010 ile 2015 yılları arasında kliniğimizde Fournier gangreni, inoperabl anorektal kanser, rektovajinal fistül ve radyoterapi nedeniyle oluşan benign striktür gibi çeşitli nedenlerle TS yapılan 14 hastanın verileri geriye doğru incelendi.Bulgular: Hastalarımızın 10’u erkek, 4’ü kadın idi. Ortalama yaşları 52.07 yıl idi. Hastalarımızdan 7 tanesine Fournier gangreni, 5 tanesine inoperabl anorektal tümör, bir tanesine kompleks rekto-vajinal fistül ve bir tanesine de almış olduğu radyoterapiye bağlı gelişen tıkayıcı striktür nedeniyle TS yapıldı. Hastalarımızın 8 tanesine rejyonel anestezi uygulandı. Tüm hastalarımıza trefin loop sigmoid kolostomi uygulandı. Bir hastamız ostomi prolapsusu nedeniyle ikinci kez opere edildi. Geçici stomalar 3 ay sonra kapatıldı. Ortalama hastanede kalış süresi 14 gün idi.Sonuç: TS görece basit, güvenli ve hızlı yapılan bir uygulama olup laparatomi endikasyonu olmayan hastalarda etkili alternatif bir yöntemdir. Düşük morbidite oranıyla acil ve elektif şartlarda uygulanabilir