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Start Over Author "Ramdas Naik" Journal journal of clinical and diagnostic research
4 results on '"Ramdas Naik"'

1. HER2 and Helicobacter pylori Status in Resected Gastric Cancers: A Pathological Study of a Gastroenterological Issue

Author

Saraswathy Sreeram, Shrijeet Chakraborti, Ramdas Naik, Debarshi Saha, Yeshwanter Radhakrishnan, Hanaganahalli Basavaiah Sridevi, Sharada Rai, and Chaithra Gowthuvalli Venkataramana

Subjects
Gastric carcinoma, Giemsa, Immunohistochemistry, HER2/neu expression, Medicine
Abstract

Introduction: Human epidermal growth factor receptor 2 (HER2)/neu is a critical target for gastric carcinoma treatment utilizing trastuzumab. Helicobacter pylori is a well known causative agent of gastric carcinoma. Aim: To study association of HER2/neu expression with the presence of H. pylori infection in resected carcinoma stomach patients. Materials and Methods: A cross-sectional study of 85 gastrectomies received in the department from January 2010 to September 2014 was done. HER2/neu was studied using Immunohistochemistry (IHC) and Giemsa stain was used to detect presence of H. pylori. Chi-square test and Fisher’s exact test were used, to test the correlation between the various parameters. A p-value

Published
2017
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2. Morphological Spectrum of Basal Cell Carcinoma in Southern Karnataka

Author

Saraswathy Sreeram, Flora Dorothy Lobo, Ramdas Naik, Urmila Niranjan Khadilkar, Hema Kini, and Ullal Anand Kini

Subjects
histopathology, skin cancer, rodent ulcer, Medicine
Abstract

Introduction: Basal Cell Carcinoma (BCC) is the most common skin cancer worldwide, which appears over sun-exposed skin as slow-growing, locally invasive lesion that rarely metastasizes. Many phenotypic presentations are possible. BCCs are more common in males and tend to occur in older people. Majority is found on the head and neck. Many histopathological subtypes have been defined including nodular, micronodular, cystic, superficial, pigmented, adenoid, infiltrating, sclerosing, keratotic, infundibulocystic, metatypical, basosquamous and fibroepitheliomatous. Mixed patterns are common. Aim: The aim was to study morphological spectrum of BCC in a tertiary care hospital in southern Karnataka. Materials and Methods: This was a retrospective analysis of 100 cases of BCCs reported in the Department of Pathology over a 9-year period from 2006 to 2014. Results: The mean age of presentation was 62 years. There was slight female preponderance (56%). The most common location was face (65%) and the most common presentation was ulceration (45%). Of the 100 BCCs, 50% were nodular, 13% infiltrating, 6% basosquamous, 4% superficial, 3% keratotic, 3% multinodular and 1% mixed. Conclusion: BCC, besides being the commonest cutaneous cancer, is also known for its numerous histological patterns which are shown to have prognostic implications. This study reveals the frequency of the various histological patterns of BCC in southern Karnataka, where it has been rarely studied before.

Published
2016
Full Text
View/download PDF

3. HER2 and Helicobacter pylori Status in Resected Gastric Cancers: A Pathological Study of a Gastroenterological Issue

Author

Yeshwanter Radhakrishnan, Chaithra Gowthuvalli Venkataramana, Ramdas Naik, H B Sridevi, Sharada Rai, Saraswathy Sreeram, Debarshi Saha, and Shrijeet Chakraborti

Subjects
0301 basic medicine, Pathology, medicine.medical_specialty, Clinical Biochemistry, lcsh:Medicine, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Trastuzumab, Carcinoma, Medicine, biology, business.industry, Stomach, lcsh:R, Gastric carcinoma, Intestinal metaplasia, Cancer, General Medicine, Helicobacter pylori, medicine.disease, biology.organism_classification, Immunohistochemistry, HER2/neu expression, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Giemsa, business, medicine.drug
Abstract

Introduction: Human epidermal growth factor receptor 2 (HER2)/neu is a critical target for gastric carcinoma treatment utilizing trastuzumab. Helicobacter pylori is a well known causative agent of gastric carcinoma. Aim: To study association of HER2/neu expression with the presence of H. pylori infection in resected carcinoma stomach patients. Materials and Methods: A cross-sectional study of 85 gastrectomies received in the department from January 2010 to September 2014 was done. HER2/neu was studied using Immunohistochemistry (IHC) and Giemsa stain was used to detect presence of H. pylori. Chi-square test and Fisher’s exact test were used, to test the correlation between the various parameters. A p-value

Published
2017

4. Morphological Spectrum of Basal Cell Carcinoma in Southern Karnataka

Author

Ramdas Naik, Ullal Anand Kini, Flora D. Lobo, Saraswathy Sreeram, Hema Kini, and Urmila N Khadilkar

Subjects
medicine.medical_specialty, Pathology, Clinical Biochemistry, lcsh:Medicine, Cutaneous cancer, Adenoid, 03 medical and health sciences, 0302 clinical medicine, Female preponderance, Pathology Section, medicine, Basal cell carcinoma, 030212 general & internal medicine, rodent ulcer, skin cancer, business.industry, lcsh:R, Mean age, 030206 dentistry, General Medicine, Tertiary care hospital, medicine.disease, medicine.anatomical_structure, histopathology, Histopathology, Skin cancer, business
Abstract

Introduction: Basal Cell Carcinoma (BCC) is the most common skin cancer worldwide, which appears over sun-exposed skin as slow-growing, locally invasive lesion that rarely metastasizes. Many phenotypic presentations are possible. BCCs are more common in males and tend to occur in older people. Majority is found on the head and neck. Many histopathological subtypes have been defined including nodular, micronodular, cystic, superficial, pigmented, adenoid, infiltrating, sclerosing, keratotic, infundibulocystic, metatypical, basosquamous and fibroepitheliomatous. Mixed patterns are common. Aim: The aim was to study morphological spectrum of BCC in a tertiary care hospital in southern Karnataka. Materials and Methods: This was a retrospective analysis of 100 cases of BCCs reported in the Department of Pathology over a 9-year period from 2006 to 2014. Results: The mean age of presentation was 62 years. There was slight female preponderance (56%). The most common location was face (65%) and the most common presentation was ulceration (45%). f the 100 BCCs, 50% were nodular, 13% infiltrating, 6% basosquamous, 4% superficial, 3% keratotic, 3% multinodular and 1% mixed. Conclusion: BCC, besides being the commonest cutaneous cancer, is also known for its numerous histological patterns which are shown to have prognostic implications. This study reveals the frequency of the various histological patterns of BCC in southern Karnataka, where it has been rarely studied before.

Published
2016

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