1. Magnetic resonance imaging findings in patients with severe neonatal indirect hyperbilirubinemia
- Author
-
Serpil Yilmaz-Degirmenci, Gamze Kilicoglu, Levent Çelik, Gülay Alper, Leyla Karadeniz, and Yüksel Yilmaz
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Globus Pallidus ,03 medical and health sciences ,0302 clinical medicine ,Neonatal Indirect Hyperbilirubinemia ,Risk Factors ,030225 pediatrics ,medicine ,Humans ,In patient ,Dominance, Cerebral ,Kernicterus ,Neurologic Examination ,medicine.diagnostic_test ,business.industry ,musculoskeletal, neural, and ocular physiology ,Infant, Newborn ,Infant ,Magnetic resonance imaging ,Jaundice ,Magnetic Resonance Imaging ,Jaundice, Neonatal ,Globus pallidus ,nervous system ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Female ,Neurology (clinical) ,Differential diagnosis ,medicine.symptom ,Abnormality ,Neurologic Findings ,business ,030217 neurology & neurosurgery ,Follow-Up Studies - Abstract
The aim of this study was to document the magnetic resonance imaging (MRI) findings of cases with a history of severe neonatal indirect hyperbilirubinemia. Ten cases (eight cases with neurologic findings, two normal cases) with a history of severe neonatal indirect hyperbilirubinemia were studied. Neurologic findings and MRI results were described and correlated. Seven of eight cases with neurologic findings demonstrated symmetric and uniform increased T2signal changes limited to globus pallidi. MRI scans of two cases without neurologic findings showed no abnormality. Severe neonatal indirect hyperbilirubinemia should be considered in the differential diagnosis of bilateral symmetric hyperintense signal changes in the globus pallidus on MRI. However, high levels of unconjugated bilirubin concentrations in the neonatal period may not always cause such lesions of globus pallidus on MRI despite the presence of neurologic findings. (J Child Neurol 2001;16:452-455).
- Published
- 2001