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Start Over Author "A., DI LENARDA" Journal journal of cardiovascular medicine
26 results on '"A., DI LENARDA"'

3. Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper

Author

Colivicchi, Furio, Di Fusco, Stefania Angela, Scicchitano, Pietro, Caldarola, Pasquale, Murrone, Adriano, Valente, Serafina, Urbinati, Stefano, Roncon, Loris, Amodeo, Vincenzo, Aspromonte, Nadia, Cipriani, Manlio, Domenicucci, Stefano, Francese, Giuseppina Maura, Imazio, Massimo, Scotto di Uccio, Fortunato, Di Lenarda, Andrea, Gulizia, Michele Massimo, and Gabrielli, Domenico

Published
2021
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5. Risk stratification and secondary prevention post-myocardial infarction: insights from the EYESHOT Post-MI study

Author

Lucio Gonzini, Pietro Scicchitano, Leonardo De Luca, Domenico Gabrielli, Pasquale Caldarola, Federico Nardi, Stefania Angela Di Fusco, Michele Massimo Gulizia, Giovanna Geraci, Andrea Di Lenarda, Eyeshot Post-MI Investigators, Furio Colivicchi, and Roberta Rossini

Subjects
Male, medicine.medical_specialty, Myocardial Infarction, MEDLINE, Aftercare, Renal function, Comorbidity, Coronary Artery Disease, 030204 cardiovascular system & hematology, Risk Assessment, Severity of Illness Index, Post myocardial infarction, 03 medical and health sciences, 0302 clinical medicine, Ezetimibe, Diabetes mellitus, Internal medicine, Secondary Prevention, medicine, Humans, 030212 general & internal medicine, Myocardial infarction, Aged, Secondary prevention, Health Services Needs and Demand, business.industry, General Medicine, medicine.disease, Italy, Heart Disease Risk Factors, Female, Risk Adjustment, Cardiology and Cardiovascular Medicine, business, Platelet Aggregation Inhibitors, medicine.drug, Kidney disease
Abstract

AIMS Clinical management of patients more than 1 year after acute myocardial infarction (MI) is challenging. Patient risk stratification may help to establish therapeutic priorities. We aimed to describe the comprehensive risk profile and management of patients with prior MI. METHODS We analyzed data from the EYESHOT Post-MI study, which evaluated the management of patients 1-3 years after MI. The risk profile of participants was defined according to the qualifying high-risk features of the PEGASUS-TIMI 54 trial (history of diabetes, history of recurrent MI, angiographic evidence of multivessel coronary disease, chronic kidney disease with estimated glomerular filtration rate

Published
2020
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6. Italian Cardiological Guidelines (COCIS) for Competitive Sport Eligibility in athletes with heart disease

Author

Delise, Pietro, primary, Mos, Lucio, additional, Sciarra, Luigi, additional, Basso, Cristina, additional, Biffi, Alessandro, additional, Cecchi, Franco, additional, Colivicchi, Furio, additional, Corrado, Domenico, additional, D’Andrea, Antonello, additional, Di Cesare, Ernesto, additional, Di Lenarda, Andrea, additional, Gervasi, Salvatore, additional, Giada, Franco, additional, Guiducci, Vincenzo, additional, Inama, Giuseppe, additional, Leoni, Loira, additional, Palamà, Zefferino, additional, Patrizi, Giampiero, additional, Pelliccia, Antonio, additional, Penco, Maria, additional, Robles, Antonio Gianluca, additional, Romano, Silvio, additional, Romeo, Francesco, additional, Sarto, Patrizio, additional, Sarubbi, Berardo, additional, Sinagra, Gianfranco, additional, and Zeppilli, Paolo, additional

Published
2021
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7. Non-high-density lipoprotein cholesterol versus low-density lipoprotein cholesterol in clinical practice: ANMCO position paper

Author

Colivicchi, Furio, primary, Di Fusco, Stefania Angela, additional, Arca, Marcello, additional, Leggio, Massimo, additional, Caldarola, Pasquale, additional, Murrone, Adriano, additional, Valente, Serafina, additional, Urbinati, Stefano, additional, Roncon, Loris, additional, Amodeo, Vincenzo, additional, Aspromonte, Nadia, additional, Cipriani, Manlio, additional, Domenicucci, Stefano, additional, Francese, Giuseppina Maura, additional, Imazio, Massimo, additional, di Uccio, Fortunato Scotto, additional, Di Lenarda, Andrea, additional, Gulizia, Michele Massimo, additional, and Gabrielli, Domenico, additional

Published
2021
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8. Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper

Author

Colivicchi, Furio, primary, Di Fusco, Stefania Angela, additional, Scicchitano, Pietro, additional, Caldarola, Pasquale, additional, Murrone, Adriano, additional, Valente, Serafina, additional, Urbinati, Stefano, additional, Roncon, Loris, additional, Amodeo, Vincenzo, additional, Aspromonte, Nadia, additional, Cipriani, Manlio, additional, Domenicucci, Stefano, additional, Francese, Giuseppina Maura, additional, Imazio, Massimo, additional, Scotto di Uccio, Fortunato, additional, Di Lenarda, Andrea, additional, Gulizia, Michele Massimo, additional, and Gabrielli, Domenico, additional

Published
2020
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10. Improving the appropriateness of sudden arrhythmic death primary prevention by implantable cardioverter-defibrillator therapy in patients with low left ventricular ejection fraction. Point of view

Author

Giancarlo Casolo, Pietro Delise, Michele Massimo Gulizia, Luisa Mestroni, Giuseppe Di Tano, Jorge A. Salerno-Uriarte, Marcello Disertori, Luigi Tavazzi, Andrea Di Lenarda, and Maurizio Lunati

Subjects
medicine.medical_specialty, animal structures, medicine.medical_treatment, Left, Reviews, Heart failure, Arrhythmias, 030204 cardiovascular system & hematology, Late gadolinium enhancement, Implantable cardioverter-defibrillator, Ventricular Dysfunction, Left, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Primary prevention, Sudden death, T-wave alternans, Arrhythmias, Cardiac, Death, Sudden, Cardiac, Humans, Primary Prevention, Stroke Volume, Defibrillators, Implantable, Cardiology and Cardiovascular Medicine, Ventricular Dysfunction, Medicine, In patient, 030212 general & internal medicine, Ejection fraction, business.industry, General Medicine, Stroke volume, medicine.disease, Arrhythmic death, Sudden, Death, Etiology, Cardiology, Implantable, business, Cardiac, Defibrillators
Abstract

It is generally accepted that the current guidelines for the primary prevention of sudden arrhythmic death, which are based on ejection fraction, do not allow the optimal selection of patients with low left ventricular ejection fraction of ischemic and nonischemic etiology for implantation of a cardioverter-defibrillator. Ejection fraction alone is limited in both sensitivity and specificity. An analysis of the risk of sudden arrhythmic death with a combination of multiple tests (ejection fraction associated with one or more arrhythmic risk markers) could partially compensate for these limitations. We propose a polyparametric approach for defining the risk of sudden arrhythmic death using ejection fraction in combination with other clinical and arrhythmic risk markers (i.e. late gadolinium enhancement cardiac magnetic resonance, T-wave alternans, programmed ventricular stimulation, autonomic tone, and genetic testing) that have been validated in nonrandomized trials. In this article, we examine these approaches to identify three subsets of patients who cannot be comprehensively assessed by the current guidelines: patients with ejection fraction of 35% or less and a relatively low risk of sudden arrhythmic death despite the ejection fraction value; patients with ejection fraction of 35% or less and high competitive risk of death due to evolution of heart failure or noncardiac causes; and patients with ejection fraction between 35 and 45% with relatively high risk of sudden arrhythmic death despite the ejection fraction value.

Published
2016
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11. Persistence on apixaban in atrial fibrillation patients: a retrospective multicentre study

Author

Verdecchia, Paolo, primary, D’Onofrio, Antonio, additional, Russo, Vincenzo, additional, Fedele, Francesco, additional, Adamo, Francesco, additional, Benedetti, Giulia, additional, Ferrante, Fabio, additional, Lodigiani, Corrado, additional, Paciullo, Francesco, additional, Aita, Adolfo, additional, Bartolini, Claudia, additional, Molini, Maria Gabriella, additional, Di Lenarda, Andrea, additional, Mazzone, Carmine, additional, Scotti, Lorenza, additional, Lanati, Elena Paola, additional, and Iorio, Arianna, additional

Published
2019
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12. Rationale for cardiopulmonary exercise test in the assessment of surgical risk

Author

Stefania Paolillo, Elisabetta Salvioni, Piergiuseppe Agostoni, Annamaria Iorio, Susanna Sciomer, Gianfranco Sinagra, Damiano Magrì, Andrea Di Lenarda, Iorio, A., Magrì, D., Paolillo, S., Salvioni, E., Di Lenarda, A., Sinagra, Gianfranco, Agostoni, P., and Sciomer, S.

Subjects
medicine.medical_specialty, cardiopulmonary exercise test, risk stratification, noncardiac surgery, MEDLINE, oxygen consumption, peri-operative risk, Exercise intolerance, Risk Assessment, Incremental exercise, Oxygen Consumption, Postoperative Complications, Cardiopulmonary exercise test, Preoperative Care, Health care, medicine, Humans, Intensive care medicine, business.industry, General Medicine, Surgical risk, Cardiovascular Diseases, Surgical Procedures, Operative, Exercise Test, Physical therapy, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Risk assessment, Anaerobic exercise
Abstract

Although in the past years a reduced mortality in peri-operative care has been observed, cardiovascular mortality and morbidity still is a major burden in patients undergoing noncardiac surgery and its evaluation is still a difficult task. An accurate risk stratification can improve quality of peri-operative care and may improve survival, while reducing healthcare costs. In clinical practice, we make our assessment of a patient's cardiac status based on history, examination and investigations, together with risks related to the surgical procedure, to generate an 'individualized cardiac risk assessment'. At the present, risk stratification with clinical risk score and cardiac testing have been shown to be suboptimal in identifying high-risk patients. Surgery, like exercise, increases oxygen consumption. Indeed, one of the key elements in determining risk assessment is exercise intolerance, but future research in this field is needed to clarify this statement. Cardiopulmonary exercise testing (CPET) provides a global assessment of functional capacity involving and integrating the physiological measurement during incremental exercise. The pattern of CPET's variables identifies the abnormal exercise capacity, often providing an objective evaluation of cause and, moreover, predicting outcomes in both apparently healthy and chronic disease populations. An anaerobic threshold VO2 above 11 ml/kg per min seems to identify individuals with a very low surgical risk even if undergoing major surgery. This review is focused on tools of risk assessment in patients undergoing noncardiac surgery and on the physiological basis for CPET in detecting patients 'at risk'.

Published
2013
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14. The progression of left ventricular systolic and diastolic dysfunctions in hypertrophic cardiomyopathy: clinical and prognostic significance

Author

Renata Korcova, Marco Merlo, Giulia Barbati, René Nangah, Andrea Di Lenarda, Gianfranco Sinagra, Bruno Pinamonti, Pinamonti, B, Merlo, M, Nangah, R, Korcova, R, Di Lenarda, A, Barbati, Giulia, and Sinagra, Gianfranco

Subjects
Male, Time Factors, etiology/mortality/physiopathology/therapy/ultrasonography, Ventricular Function, medicine.medical_treatment, Left, Cardiomyopathy, Ventricular Function, Left, Ventricular Dysfunction, Left, Diastole, Risk Factors, Odds Ratio, Ventricular Dysfunction, Ventricular Function, Heart transplantation, Ejection fraction, Doppler, Female, Heart Transplantation, Humans, Italy, Logistic Models, Male, Middle Aged, Odds Ratio, Proportional Hazards Models, Risk Assessment, Risk Factors, Survival Analysis, Systole, Time Factors, Treatment Outcome, Ventricular Dysfunction, Hazard ratio, Doppler, Hypertrophic cardiomyopathy, General Medicine, Middle Aged, Echocardiography, Doppler, Adult, Cardiomyopathy, Hypertrophic, complications/mortality/physiopathology/therapy/ultrasonography, Diastole, Disease Progression, Echocardiography, Left, Young Adult, Treatment Outcome, Italy, Echocardiography, etiology/mortality/physiopathology/therapy/ultrasonography, Disease Progression, cardiovascular system, Cardiology, Female, Cardiology and Cardiovascular Medicine, Adult, medicine.medical_specialty, Systole, Risk Assessment, Young Adult, Internal medicine, medicine, Humans, cardiovascular diseases, Proportional Hazards Models, business.industry, Cardiomyopathy, Hypertrophic, medicine.disease, Survival Analysis, Transplantation, Logistic Models, complications/mortality/physiopathology/therapy/ultrasonography, Heart Transplantation, business
Abstract

Objectives The significance of the progression of systolic and diastolic dysfunctions in hypertrophic cardiomyopathy (HCM) is still an open issue. We sought to evaluate the clinical and prognostic implications of the progression of left ventricular systolic and diastolic dysfunction in HCM. Methods One hundred one HCM patients were studied by echo-Doppler at baseline and during follow-up. Results During a follow-up of 109W67 months, 28% of patients showed a progression to left ventricular diastolic dysfunction, defined as restrictive filling pattern (RFP), and 16% to left ventricular systolic dysfunction (left ventricular ejection fraction

Published
2010
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16. Atrial fibrillation, cognitive impairment, frailty and disability in older heart failure patients

Author

Pulignano, Giovanni, primary, Del Sindaco, Donatella, additional, Tinti, Maria D., additional, Di Lenarda, Andrea, additional, Alunni, Gianfranco, additional, Senni, Michele, additional, Tarantini, Luigi, additional, Cioffi, Giovanni, additional, Barbati, Giulia, additional, Minardi, Giovanni, additional, Murrone, Adriano, additional, Ciurluini, Paola, additional, and Uguccioni, Massimo, additional

Published
2016
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17. Improving the appropriateness of sudden arrhythmic death primary prevention by implantable cardioverter-defibrillator therapy in patients with low left ventricular ejection fraction. Point of view

Author

Disertori, Marcello, primary, Gulizia, Michele M., additional, Casolo, Giancarlo, additional, Delise, Pietro, additional, Di Lenarda, Andrea, additional, Di Tano, Giuseppe, additional, Lunati, Maurizio, additional, Mestroni, Luisa, additional, Salerno-Uriarte, Jorge, additional, and Tavazzi, Luigi, additional

Published
2016
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22. Natural history of dilated cardiomyopathy: from asymptomatic left ventricular dysfunction to heart failure – a subgroup analysis from the Trieste Cardiomyopathy Registry

Author

Aleksova, Aneta, primary, Sabbadini, Gastone, additional, Merlo, Marco, additional, Pinamonti, Bruno, additional, Barbati, Giulia, additional, Zecchin, Massimo, additional, Bussani, Rossana, additional, Silvestri, Furio, additional, Iorio, Anna M, additional, Stolfo, Davide, additional, Dal Ferro, Matteo, additional, Dragos, Andreea M, additional, Meringolo, Gennaro, additional, Pyxaras, Stelios, additional, Lo Giudice, Francesco, additional, Perkan, Andrea, additional, di Lenarda, Andrea, additional, and Sinagra, Gianfranco, additional

Published
2009
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23. The challenge of cardiomyopathies in 2007

Author

Sinagra, Gianfranco, primary, Di Lenarda, Andrea, additional, Moretti, Michele, additional, Mestroni, Luisa, additional, Pinamonti, Bruno, additional, Perkan, Andrea, additional, Salvi, Alessandro, additional, Pyxaras, Stylianos, additional, Bussani, Rossana, additional, Silvestri, Furio, additional, and Camerini, Fulvio, additional

Published
2008
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24. Baseline characteristics of patients recruited in the AREA IN-CHF study (Antiremodelling Effect of Aldosterone Receptors Blockade with Canrenone in Mild Chronic Heart Failure)

Author

Boccanelli, Alessandro, primary, Cacciatore, Giuseppe, additional, Mureddu, Gian Francesco, additional, de Simone, Giovanni, additional, Clemenza, Francesco, additional, De Maria, Renata, additional, Di Lenarda, Andrea, additional, Gavazzi, Antonello, additional, Latini, Roberto, additional, Masson, Serge, additional, Porcu, Maurizio, additional, Vanasia, Massimo, additional, Gonzini, Lucio, additional, and Maggioni, Aldo Pietro, additional

Published
2007
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