1. Outcomes following persistent atrial fibrillation ablation using localized sources identified with Ripple map
- Author
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John S. Zakaib, Jo Ellyn Moore, Charles C. Gornick, Manju Pai, David G. Benditt, Daniel P. Melby, Raed Abdelhadi, and Jay Sengupta
- Subjects
Male ,Subset Analysis ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Ripple ,Action Potentials ,Catheter ablation ,030204 cardiovascular system & hematology ,outcomes ,Pulmonary vein ,Clinical ,03 medical and health sciences ,0302 clinical medicine ,Heart Rate ,Predictive Value of Tests ,Recurrence ,Risk Factors ,Physiology (medical) ,Internal medicine ,catheter ablation ,Atrial Fibrillation ,medicine ,Humans ,030212 general & internal medicine ,Atrial tachycardia ,Aged ,Retrospective Studies ,business.industry ,Atrial fibrillation ,Original Articles ,Middle Aged ,medicine.disease ,Ablation ,Ripple map ,Progression-Free Survival ,Pulmonary Veins ,Persistent atrial fibrillation ,Cardiology ,Original Article ,Female ,medicine.symptom ,Electrophysiologic Techniques, Cardiac ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Ablation of persistent atrial fibrillation (AF) remains challenging. Identification and ablation of localized AF drivers may offer the possibility for improved outcomes. Ripple map is a novel software algorithm that may allow improved localization of possible AF drivers through the whole chamber graphical display of continuously recorded bipolar electrograms. The objective of this study was to determine whether regions of high‐frequency Ripple activation (HFRA) observed on Ripple map provide useful ablation targets in patients with persistent AF. Methods and Results Consecutive patients underwent the first‐time ablation of persistent AF (n = 162) using a standard stepwise (n = 105) or a Ripple map guided approach (n = 57). Ripple map guided patients underwent pulmonary vein antral isolation followed by ablation of HFRA sites. Acute termination of AF was observed in 91.2% of the Ripple‐guided patients vs 52.4% in the stepwise approach, P
- Published
- 2019
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