1. Social attainment in survivors of pediatric central nervous system tumors: a systematic review and meta-analysis from the Children’s Oncology Group
- Author
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Alicia Kunin-Batson, Kevin R. Krull, Pia Banerjee, Barbara A. Olson-Bullis, Lisa S. Kahalley, Hayley Wroot, Caitlin Forbes, Laura Janzen, Fiona Schulte, and Matthew C. Hocking
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pediatrics ,Adolescent ,Hearing loss ,Psychological intervention ,PsycINFO ,Article ,Central Nervous System Neoplasms ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Survivorship curve ,Humans ,Medicine ,Survivors ,030212 general & internal medicine ,Child ,Oncology (nursing) ,business.industry ,Public health ,Educational attainment ,Oncology ,Child, Preschool ,030220 oncology & carcinogenesis ,Meta-analysis ,Female ,medicine.symptom ,business ,Social Adjustment ,Neurocognitive - Abstract
PURPOSE: Improved therapies for pediatric central nervous system (CNS) tumors have increased survival rates, however, many survivors experience significant long-term functional limitations. Survivors of pediatric CNS tumors can experience deficits in social attainment. The aim of this review was to systematically amalgamate findings pertaining to social attainment (i.e., educational attainment, marriage, employment outcomes) in survivors of pediatric CNS tumors. METHODS: PubMed(Web-based), PsycINFO(EBSCO), EMBASE(Ovid), and Web of Science(Thomson Reuters) were used to identify articles published between January 2011 and September 2018. Eligible studies reported outcomes for survivors of pediatric CNS tumors diagnosed before age 21 years, and >5 years from diagnosis and/or >2 years off therapy. All data were independently abstracted by two reviewers. Random-effects meta-analyses were performed using Review Manager 5.0. RESULTS: The search yielded 7,021 unique publications. Forty-six were included in the current review. Meta-analyses revealed survivors of CNS tumors were significantly more likely to have completed compulsory education only (OR = 1.87, 95% CI = 1.66, 2.12, p < 0.00001), less likely to be married (OR = 4.70, 95% CI = 3.89, 5.68, p
- Published
- 2019
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