1. Tissue repair strength using chitosan adhesives with different physical-chemical characteristics
- Author
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Richard Wuhrer, Antonio Lauto, John W. Morley, David Fania, Samuel J Frost, Matthew J. Barton, Damia Mawad, Christian Loebbe, and David A. Mahns
- Subjects
Materials science ,technology, industry, and agriculture ,General Engineering ,General Physics and Astronomy ,Chemical modification ,Biomaterial ,macromolecular substances ,General Chemistry ,Tissue repair ,equipment and supplies ,General Biochemistry, Genetics and Molecular Biology ,carbohydrates (lipids) ,Chitosan ,chemistry.chemical_compound ,chemistry ,Bonding strength ,Physical chemical ,Ultimate tensile strength ,Polymer chemistry ,General Materials Science ,Adhesive ,Composite material - Abstract
A range of chitosan–based biomaterials have recently been used to perform sutureless, laser-activated tissue repair. Laser-activation has the advantage of bonding to tissue through a non-contact, aseptic mechanism. Chitosan adhesive films have also been shown to adhere to sheep intestine strongly without any chemical modification to chitosan. In this study, we continue to investigate chitosan adhesive films and explore the impact on the tissue repair strength and tensile strength characteristics of four types of adhesive film based on chitosan with different molecular weight and degree of deacetylation. Results showed that adhesives based on chitosan with medium molecular weight achieved the highest bonding strength, tensile strength and E-modulus when compared to the other adhesives. (© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
- Published
- 2014
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