1. Monitoring remineralization of enamel subsurface lesions by optical coherence tomography
- Author
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Mona M. Mandurah, Junji Tagami, Yasunori Sumi, Alireza Sadr, Turki A. Bakhsh, Yuichi Kitasako, Yasushi Shimada, and Syozi Nakashima
- Subjects
Materials science ,Biomedical Engineering ,Dentistry ,Biomaterials ,Fluorides ,stomatognathic system ,Optical coherence tomography ,Hardness ,medicine ,Animals ,Dental Enamel ,Tooth Demineralization ,Remineralisation ,Analysis of Variance ,Enamel paint ,medicine.diagnostic_test ,business.industry ,Attenuation ,Tooth Remineralization ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Demineralization ,visual_art ,Attenuation coefficient ,visual_art.visual_art_medium ,Linear Models ,Calcium ,Cattle ,Tomography ,business ,Tomography, Optical Coherence ,Biomedical engineering - Abstract
Optical coherence tomography (OCT) is a potential clinical tool for enamel lesion monitoring. Swept-source OCT findings were compared with cross-sectional nanohardness findings of enamel. Subsurface bovine enamel lesions in three groups were subjected to (1) deionized water (control), (2) phosphoryl oligosaccharide of calcium (POs-Ca) or (3) POs-Ca with 1 ppm fluoride for 14 days. B-scans images were obtained at 1310-nm center wavelength on sound, demineralized and remineralized areas after 4, 7, and 14 days. The specimens were processed for cross-sectional nanoindentation. Reflectivity from enamel that had increased with demineralization decreased with remineralization. An OCT attenuation coefficient parameter (μt), derived based on the Beer-Lambert law as a function of backscatter signal slope, showed a strong linear regression with integrated nanohardness of all regions (p
- Published
- 2013