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Your search keyword '"Tangier Disease metabolism"' showing total 12 results

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12 results on '"Tangier Disease metabolism"'

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1. Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.

2. Characterization of cholesterol homeostasis in telomerase-immortalized Tangier disease fibroblasts reveals marked phenotype variability.

3. Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.

4. Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism.

5. Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway.

6. ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.

7. The establishment of telomerase-immortalized Tangier disease cell lines indicates the existence of an apolipoprotein A-I-inducible but ABCA1-independent cholesterol efflux pathway.

8. Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter.

9. Impaired ABCA1-dependent lipid efflux and hypoalphalipoproteinemia in human Niemann-Pick type C disease.

10. Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate.

11. ATP-binding cassette transporter A1 mediates cellular secretion of alpha-tocopherol.

12. Endocytosis is enhanced in Tangier fibroblasts: possible role of ATP-binding cassette protein A1 in endosomal vesicular transport.

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