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1. Repression of 92-kDa Type IV Collagenase Expression by MTA1 Is Mediated through Direct Interactions with the Promoter via a Mechanism, Which Is Both Dependent on and Independent of Histone Deacetylation.

Author

Chunhong Yan, Heng Wang, Toh, Yasushi, and Boyd, Douglas D.

Subjects
*COLLAGENASES, *GENES, *HISTONE deacetylase
Abstract

Discusses a mechanism that mediated the repression of 92-kDa type IV collagenase (MMP-9) expression by metastases-associated gene MTA1. Finding that MTA1 binds to the MMP-9 promoter; Repression of expression of such type of IV collagenase via histone-dependent and independent mechanism.

Published
2003
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