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The growth and decline of yin and yang, and the conflict between healthy qi and pathogenic factor are important theoretical foundations for traditional Chinese medicine (TCM) to interpret disease occurrence and development, which is of significance for guiding the understanding of "inflammation to cancer" of chronic gastritis and its prevention and treatment. From the perspective of Western medicine, the imbalance of the immune system is the root cause of tumors, and immunotherapy is hailed as the most promising means for curing cancer. The theories of yin and yang, and healthy qi and pathogenic factor of TCM have much in common with the understanding of immunity in western medicine. Especially in recent years, the idea that tumor immunotherapy should return from " immune enhancement '' to " immune normalization" is similar to the core idea of " harmonizing yin and yang, reinforcing healthy qi to dispel pathogenic qi" in TCM. Based on the combination of theories from both traditional Chinese medicine and Western medicine, this paper aims to promote the theoretical integration and development of traditional Chinese medicine and Western medicine in prevention and treatment of inflammation to cancer" of chronic gastritis. [ABSTRACT FROM AUTHOR]