1. Brief Report: Evaluation of the Short Quantitative Checklist for Autism in Toddlers (Q-CHAT-10) as a Brief Screen for Autism Spectrum Disorder in a High-Risk Sibling Cohort
- Author
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Caroline Roncadin, Wendy Roberts, Sarah Raza, Lori-Ann R. Sacrey, Tracy Vaillancourt, Nancy Garon, Lonnie Zwaigenbaum, Isabel M. Smith, Susan E. Bryson, Kyle B Reid, Jessica Brian, and Peter Szatmari
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Autism Spectrum Disorder ,Checklist for Autism in Toddlers ,Child Behavior ,Test validity ,behavioral disciplines and activities ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,mental disorders ,Developmental and Educational Psychology ,medicine ,Humans ,Mass Screening ,0501 psychology and cognitive sciences ,Genetic Predisposition to Disease ,Sibling ,Family history ,Siblings ,digestive, oral, and skin physiology ,05 social sciences ,Infant ,Report evaluation ,medicine.disease ,Checklist ,Autism spectrum disorder ,Child, Preschool ,Cohort ,Autism ,Female ,Psychology ,030217 neurology & neurosurgery ,050104 developmental & child psychology - Abstract
This study examined the potential of the short form of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10) to identify autism spectrum disorder (ASD) in a high-risk sibling cohort. High-risk (HR; siblings of children diagnosed with ASD) and low-risk (LR; no family history of ASD) toddlers were assessed prospectively at 18 and 24 months of age using the Q-CHAT-10 and underwent blind diagnostic assessment for ASD at 36 months of age. The results indicated that at 18 and 24 months, total score differentiated between HR toddlers subsequently diagnosed with ASD from other HR and LR toddlers. The sensitivity at both time points was acceptable; however, the specificity was below the level recommended for clinical application.
- Published
- 2019