1. Atrial Fibrillation and Mild Cognitive Impairment, Examining the Prevalence, Pathological Mechanisms, and Screening Tools: A Scoping Review.
- Author
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Kirwan, Ellen, MacGilchrist, Claire, Canty, Emma, and McIntosh, Caroline
- Subjects
- *
ATRIAL fibrillation , *ARRHYTHMIA , *STROKE , *MILD cognitive impairment , *CEREBRAL infarction , *WHITE matter (Nerve tissue) - Abstract
Background: Atrial Fibrillation (AF) is the most common arrhythmia globally in adults and is associated with an increased risk of stroke, morbidity and mortality. There is growing evidence that AF is associated with mild cognitive impairment (MCI). The incidence of both conditions increase with age and both conditions share important risk factors. Objectives: This study aimed to examine the relationship between MCI and AF. The aims of this scoping review is 1) To describe the prevalence of MCI in patients with AF without prior stroke 2) To investigate the pathogenetic mechanisms linking MCI and AF and 3) To examine current screening tools employed to identify MCI. Methods: This scoping review was carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping reviews (PRISMA-ScR). Results: The scoping review included 40 studies. Across the included articles, the mean prevalence of MCI in patients with AF was 36.74%. The main proposed pathologic mechanisms linking MCI and AF were white matter lesions, cardiovascular risk factors, silent cerebral infarction and cerebral hypoperfusion. The most common tools used in these studies to identify MCI were a battery of cognitive tests and the MoCA test. [ABSTRACT FROM AUTHOR]
- Published
- 2023