1. A novel triterpenoid saponin from Polygala tenuifolia Willd
- Author
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Sheng-Xiu Xie, Dong-Ming Xu, Hong-Feng Zhao, Yu Li, Ya-Juan Xu, Tun-Hai Xu, Dong Han, Jian-Zhao Niu, Gang Lv, and Yun-Shan Si
- Subjects
Polygala ,Stereochemistry ,Saponin ,Pharmaceutical Science ,Pharmacognosy ,Plant Roots ,Analytical Chemistry ,Triterpene ,Drug Discovery ,Triterpenoid saponin ,Pharmacology ,chemistry.chemical_classification ,Molecular Structure ,biology ,Organic Chemistry ,Glycoside ,General Medicine ,Saponins ,biology.organism_classification ,Triterpenes ,Terpenoid ,Complementary and alternative medicine ,chemistry ,Polygala tenuifolia ,Molecular Medicine ,Polygalaceae - Abstract
A new triterpenoid saponin, tenuifoside A, was isolated together with three known triterpenoid saponins 2, 3, and 4 from the roots of Polygala tenuifolia Willd. With the help of chemical and spectral analyses (IR, MS, 1D-NMR, and 2D-NMR), the structure of the new saponin was elucidated as 3-O-beta-d-glucopyranosyl presenegenin 28-O-beta-d-xylopyranosyl-(1 --3)-beta-d-xylopyranosyl-(1 --4)-[beta-D-apiofuranosyl-(1 --3)]-alpha-L-rhamnopyranosyl-(1 --2)-[4-O-p-methoxycinnamoyl]-[alpha-l-rhamnopyranosyl-(1 --3)]-beta-d-fucopyranosyl ester (1). Three known triterpenoid saponins (2-4) were identified on the basis of spectroscopic data.
- Published
- 2008