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Five new oleanane-type triterpenoid saponins, oleiferasaponins D1-D5 (1-5), were isolated from the defatted seeds of Camellia oleifera Abel. Their structures were elucidated by spectroscopic and chemical methods. The cytotoxic activities of compounds 1-5 were evaluated against five human tumor cell lines (HCT-116, HepG2, BGC-823, NCI-H1650, and A2780). Compounds 1-2 exhibited cytotoxic activity against five human cancer cell lines, with IC50 values ranging from 3.31 to 10.23 μM. Compounds 3-5 showed moderate cytotoxic activities toward the tested cell lines. [ABSTRACT FROM AUTHOR]

Three new isocoumarins, terrecoumarins A–C (1–3), together with six known isocoumarins (4–9) were isolated from the fermentation products of the fungusPenicillium oxalicum0403. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of1–9were evaluated. The results revealed that compound1showed high anti-TMV activity with inhibition rate 25.4 ± 3.5%. Other compounds also showed weak activity with inhibition rate in the range of 11.3–18.9%. [ABSTRACT FROM PUBLISHER]

Two new triterpenoids, 2α,3β,16α,19α,23-pentahydroxyolean-12-en-28-oic acid (1) and 2α,3α,11α,21α,23-pentahydroxyurs-12-en-28-oic acid (2), were isolated from the aerial parts ofCallicarpa kwangtungensis. Their structures were elucidated by 1D and 2D analyses, as well as MS and IR spectra. [ABSTRACT FROM PUBLISHER]