1. Anti-inflammatory lupane triterpenoids from Menyanthes trifoliata
- Author
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Zheng-Hui Li, Jiao-Jiao Zhu, Ji-Kai Liu, Hui-Xiang Yang, Guo-Kai Wang, and Tao Feng
- Subjects
Pharmacology ,Gentianaceae ,biology ,Menyanthes ,010405 organic chemistry ,Chemistry ,medicine.drug_class ,Stereochemistry ,Organic Chemistry ,Pharmaceutical Science ,General Medicine ,biology.organism_classification ,01 natural sciences ,Anti-inflammatory ,0104 chemical sciences ,Analytical Chemistry ,010404 medicinal & biomolecular chemistry ,Triterpenoid ,Complementary and alternative medicine ,Drug Discovery ,medicine ,Molecular Medicine ,Two-dimensional nuclear magnetic resonance spectroscopy - Abstract
A new lupane triterpenoid, 23-O-trans-feruloylcylicodiscic acid (1), as well as four known analogues (2‒5), was isolated from the EtOAc fraction of Menyanthes trefoliata. The structure of compound 1 was elucidated on the basis of extensive spectroscopic analysis, including 2D NMR data. The structures of the known compounds were established by comparison of their spectroscopic data with that in the literature. Compounds 1, 2, and 4 exhibited certain anti-NO production activities.
- Published
- 2018
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