1. Three new chromanes and one new flavone C-glycoside from Mallotus apelta
- Author
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Anh, Nguyen Hoang, Yen, Duong Thi Hai, Nguyen The Cuong, Tai, Bui Huu, Yen, Pham Hai, Pham The Chinh, Van Cuong, Pham, Nam, Nguyen Hoai, Van Kiem, Phan, Cho, Su-Hyeon, Park, SeonJu, and Nhiem, Nguyen Xuan
- Subjects
Pharmacology ,Complementary and alternative medicine ,Organic Chemistry ,Drug Discovery ,Pharmaceutical Science ,Molecular Medicine ,General Medicine ,Analytical Chemistry - Abstract
Three new chromanes, malloapeltas J–L (1–3), and one new flavone C-glycoside, malloflavoside (4), together with four known compounds, apigenin 6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside (5), apigenin 6-C-β-D-glucopyranosyl-8-C-α-L-arabinopyranoside (6), apigenin 7-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside (7), and acantrifoside E (8) were isolated from the methanol extract of the leaves of Mallotus apelta. Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.
- Published
- 2022
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