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Your search keyword '"Liu, Yan"' showing total 2 results
2 results on '"Liu, Yan"'

1. Two new iridoid glycosides from the whole plant of Rehmania piasezkii.

Author

Zhou, Jie, Shi, Guo-Ru, Zhang, Wan-Qi, Yu, De-Quan, and Liu, Yan-Fei

Subjects
CHINESE medicine, RESEARCH funding, NUCLEAR magnetic resonance spectroscopy, HERBAL medicine, SPECTROPHOTOMETERS, THIN layer chromatography, DESCRIPTIVE statistics, PLANT extracts, CELL lines, MEDICINAL plants, GLYCOSIDES, MOLECULAR structure, BIOLOGICAL assay, HEPATOCELLULAR carcinoma, ACETAMINOPHEN
Abstract

Two new iridoid glycosides, piasezkiiosides A (1) and B (2), were isolated from aqueous extract of the whole plant of Rehmannia piasezkii. Their structures were established from the spectroscopic data, chemical transformation, and X-ray diffraction analysis. Compound 1 exhibited weak hepatoprotective activity against APAP-induced HepG2 cell damage. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Four new iridoid glycosides from the roots of Rehmannia glutinosa.

Author

Liu, Yan-Fei, Zhang, Wan-Qi, Zhou, Jie, Shi, Guo-Ru, Li, Xin-Yue, Sun, Ming-Hui, Chen, Ruo-Yun, and Yu, De-Quan

Subjects
*CHINESE medicine, *RESEARCH funding, *CELL proliferation, *HEXOSES, *PLANT roots, *DESCRIPTIVE statistics, *PLANT extracts, *CELL lines, *GLYCOSIDES, *MEDICINAL plants, *MOLECULAR structure, *LACTOBACILLUS
Abstract

Four new iridoid glycosides (1–4), rehmaglutosides L–O, were isolated from the air-dried roots of Rehmannia glutinosa. Their structures were established from the spectroscopic data obtained and by chemical evidence. The known mellittoside (5) and ajugol (6) were also obtained in the current investigation, and the structure of mellittoside was unequivocally defined using X-ray diffraction data. Compounds 1–6 were tested for their cytotoxicity against five human tumor cell lines and proliferation effects on Lactobacillus Reuteri. [ABSTRACT FROM AUTHOR]

Published
2024
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