1. Antimicrobial limonoids from the seeds of Cipadessa cinerascensa.
- Author
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Ya-Nan Tong, Jia Guo, Yu-Feng Chen, and Guo-Xu Zhang
- Subjects
IN vitro studies ,MEDICINAL plants ,ANTI-infective agents ,NUCLEAR magnetic resonance spectroscopy ,HYDROCARBONS ,PHYTOCHEMICALS ,SEEDS ,MOLECULAR structure ,PLANT extracts ,PHARMACODYNAMICS - Abstract
Phytochemical investigation on the 90% EtOH extract of the seeds of Cipadessa cinerascensa led to the isolation of three new limonoids, cinerascenoids A-C (1-3). Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (¹H-¹H COSY, HMQC, and HMBC) NMR spectroscopy. All the limonoids were in vitro evaluated for their antimicrobial activities against six pathogenic microorganisms. Limonoids 1 and 2 exhibited some activities against three Gram negative bacteria with MIC values less than 60μg/ml. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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