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[Display omitted] • The ca. 311 Ma granite was derived from biotite dehydration melting of metagreywacke. • The ca. 283 Ma granite experienced extreme differentiation and melt–fluid interaction. • The granitic rocks record the tectonic transition from syn- to post-collision (ca. 320–280 Ma). • Hf isotopic mapping reveals significant crustal reworking. Peraluminous granitoids can provide crucial insights into crustal reworking. Here we report a geochemical study of two Late Paleozoic peraluminous granitic plutons in the South Tianshan Belt, NW China, to constrain their crustal reworking history. Zircon U-Pb analyses yield ages of 311 ± 4 Ma for the garnet-bearing biotite granite and 283 ± 4 Ma for the garnet-bearing muscovite granite. The garnet-bearing biotite granites exhibit peraluminous affinity (ASI = 1.04–1.11), high CaO/Na 2 O, low Rb/Sr, and negative ε Nd (t) (−8.7 to –7.5) and zircon ε Hf (t) (–8.4 to –0.8) values with ancient crustal model ages, which suggest they were derived from dehydration melting of metagraywacke. The garnet-bearing muscovite granites, containing manganese garnet, show high SiO 2 (72.3–76.8 wt%) and strongly peraluminous (ASI = 1.14–1.22), high Rb/Sr (37.8–128.9), low Zr/Hf (16.61–31.80) and Nb/Ta (3.05–5.71), and exhibit tetrad REE patterns (TE 1 , 3 = 1.05–1.27), which can be ascribed to high-degree fractional crystallization accompanied by the interaction with fluids. They show negative ε Nd (t) values (–8.6 to –6.6) and variable zircon ε Hf (t) values (–4.9 to +2.7), implying ancient crustal with minor juvenile crustal sources. In combination with the occurrence of peraluminous magmatic rocks of the South Tianshan Belt, we propose that the peraluminous magmatic rocks were formed by the partial melting of ancient crustal rocks from the passive continental margin of the Tarim Craton, which represents an important crustal reworking event in the Central Asian Orogenic Belt. [ABSTRACT FROM AUTHOR]