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Your search keyword '"Benjamin J. Ryan"' showing total 3 results
Start Over Author "Benjamin J. Ryan" Journal journal of applied physiology (bethesda, md. : 1985)
3 results on '"Benjamin J. Ryan"'

1. Commentaries on Viewpoint: Using V̇o

Author

Pedro L, Valenzuela, Manuel, Mateo-March, Xabier, Muriel, Mikel, Zabala, Alejandro, Lucia, David, Barranco-Gil, Grégoire P, Millet, Franck, Brocherie, Johannes, Burtscher, Martin, Burtscher, Benjamin J, Ryan, Rachel A, Gioscia-Ryan, Stephane, Perrey, Víctor, Rodrigo-Carranza, Fernando, González-Mohíno, José María, González-Ravé, Jordan, Santos-Concejero, Benedito S, Denadai, Camila C, Greco, Arturo, Casado, Carl, Foster, Raffaele, Mazzolari, Giulia Nicole, Baldrighi, Elisa, Pastorio, Davide, Malatesta, Aurélien, Patoz, Fabio, Borrani, Stephen J, Ives, Justin A, DeBlauw, Ricardo, Dantas de Lucas, Fernando Klitzke, Borszcz, Eduardo Marcel, Fernandes Nascimento, Luiz Guilherme, Antonacci Guglielmo, Tiago, Turnes, Richard T, Jaspers, Stephan, van der Zwaard, Romuald, Lepers, Julien, Louis, Anderson, Meireles, Hiago L. R., de Souza, Géssyca T, de Oliveira, Marcelo P, dos Santos, Rhaí A, Arriel, Moacir, Marocolo, B, Hunter, S, Meyler, D, Muniz-Pumares, Renato M, Ferreira, Abigail S, Sogard, Stephen J, Carter, Timothy D, Mickleborough, Guilherme Pereira, Saborosa, Raphael Dinalli, de Oliveira Freitas, Paula Souza, Alves dos Santos, João Pedro, de Souza Ferreira, Francisco, de Assis Manoel, Sandro Fernandes, da Silva, Christoph, Triska, Bettina, Karsten, Dajo, Sanders, Elliot S, Lipksi, David J, Spindler, Matthijs K. C., Hesselink, Rodrigo, Zacca, Márcio Fagundes, Goethel, David Bruce, Pyne, Brayden M, Wood, Peyton E, Allen, Jaden L, Gabelhausen, Alexandra M, Keller, Mast T, Lige, Alicia S, Oumsang, Greg L, Smart, Hunter L, Paris, Arthur H, Dewolf, Guillaume, Toffoli, Borja, Martinez-Gonzalez, Samuele M, Marcora, Daniela, Terson de Paleville, Ricardo J, Fernandes, Susana M, Soares, J. Arturo, Abraldes, Guilherme, Matta, Arthur Henrique, Bossi, D G, McCarthy, W, Bostad, J, Gibala, and Mary, Vagula

Subjects
Athletes, Physical Endurance, Humans
Published
2022

3. Inflammation and metabolism gene sets in subcutaneous abdominal adipose tissue are altered 1 hour after exercise in adults with obesity

Author

Toree C. Baldwin, Michael W. Schleh, Benjamin J. Ryan, Jenna B. Gillen, Cheehoon Ahn, Natalie M. Taylor, Jeffrey F. Horowitz, Alison C. Ludzki, Emily M. Krueger, and Pallavi Varshney

Subjects
Adult, medicine.medical_specialty, Physiology, Abdominal Fat, Subcutaneous Fat, Adipose tissue, Inflammation, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, medicine, Humans, Obesity, Exercise, 030304 developmental biology, 0303 health sciences, business.industry, Gene sets, Metabolism, medicine.disease, Endocrinology, Adipose Tissue, Female, medicine.symptom, business, Single session, 030217 neurology & neurosurgery, Research Article
Abstract

Although the health benefits of exercise in adults with obesity are well described, the direct effects of exercise on adipose tissue that may lead to improved metabolic health are poorly understood. The primary aims of this study were to perform an unbiased analysis of the subcutaneous abdominal adipose tissue transcriptomic response to acute exercise in adults with obesity, and to compare the effects of moderate-intensity continuous exercise versus high-intensity interval exercise on this response. Twenty-nine adults with obesity performed a session of either high-intensity interval exercise (HI; 10 × 1 min at 90%HRpeak, 1 min recovery between intervals; n = 14) or moderate-intensity continuous exercise (MI; 45 min at 70%HRpeak; n = 15). Groups were well matched for BMI (HI 33 ± 3 vs. MI 33 ± 4 kg/m(2)), sex (HI: 9 women vs. MI: 10 women), and age (HI: 32 ± 6 vs. MI: 29 ± 5). Subcutaneous adipose tissue was collected before and 1 h after the session of HI or MI, and samples were processed for RNA sequencing. Gene set enrichment analysis revealed 7 of 21 gene sets enriched postexercise overlapped between HI and MI. Interestingly, both HI and MI upregulated gene sets involved in inflammation (IL6-JAK-STAT3 signaling, allograft rejection, TNFα signaling via NFκB, and inflammatory response; FDR q value < 0.25). Exercise also downregulated adipogenic and oxidative metabolism gene sets in both groups. Overall, these data suggest genes involved in subcutaneous adipose tissue metabolism and inflammation may be an important part of the initial response after a session of exercise. NEW & NOTEWORTHY This study compared the effects of a single session of high-intensity interval exercise versus moderate-intensity continuous exercise on transcriptional changes in subcutaneous abdominal adipose tissue collected from adults with obesity. Our novel findings indicate exercise upregulated inflammation-related gene sets, while it downregulated metabolism-related gene sets – after both high-intensity and moderate-intensity exercise. These data suggest exercise can alter the adipose tissue transcriptome 1 h after exercise in ways that may impact inflammation and metabolism.

Published
2021

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