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Your search keyword '"Mccarthy, John J"' showing total 13 results
Start Over Author "Mccarthy, John J" Journal journal of applied physiology
13 results on '"Mccarthy, John J"'

4. Commentaries on Viewpoint: The rigorous study of exercise adaptations: Why mRNA might not be enough

Author

Hornberger, Troy A., Carter, Heather N., Hood, David A., Figueiredo, Vandré Casagrande, Dupont-Versteegden, Esther E., Peterson, Charlotte A., McCarthy, John J., Camera, Donny M., Hawley, John A., Chaillou, Thomas, Cheng, Arthur J., Nader, Gustavo A., Wüst, Rob C. I., Houtkooper, Riekelt H., Other departments, Amsterdam Gastroenterology Endocrinology Metabolism, and Laboratory Genetic Metabolic Diseases

Subjects
0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Physiology, Physiology (medical), Integrative biology, Cellular level, Biology, Whole body, Neuroscience
Abstract

Integrative biology is needed to understand exercise adaptions from the whole body to the cellular level

Published
2016

7. MyoVision: software for automated high-content analysis of skeletal muscle immunohistochemistry.

Author

Yuan Wen, Murach, Kevin A., Vechetti Jr., Ivan J., Fry, hristopher S., Vickery, Chase, Peterson, Charlotte A., McCarthy, John J., and Campbell, Kenneth S.

Subjects
SKELETAL muscle, IMMUNOHISTOCHEMISTRY, FLUORESCENCE microscopy
Abstract

Analysis of skeletal muscle cross sections is an important experimental technique in muscle biology. Many aspects of immunohistochemistry and fluorescence microscopy can now be automated, but most image quantification techniques still require extensive human input, slowing progress and introducing the possibility of user bias. MyoVision is a new software package that was developed to overcome these limitations. The software improves upon previously reported automatic techniques and analyzes images without requiring significant human input and correction. When compared with data derived by manual quantification, MyoVision achieves an accuracy of ≥94% for basic measurements such as fiber number, fiber type distribution, fiber cross-sectional area, and myonuclear number. Scientists can download the software free from www.MyoVision.org and use it to automate the analysis of their own experimental data. This will improve the efficiency and consistency of the analysis of muscle cross sections and help to reduce the burden of routine image quantification in muscle biology. [ABSTRACT FROM AUTHOR]

Published
2018
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13. IGF-1 IS NOT KEY FOR ADULT SKELETAL MUSCLE HYPERTROPHY.

Author

Esser, Karyn A., McCarthy, John J., and Miyazaki, Mitsunori

Subjects
LETTERS to the editor, GROWTH factors, MUSCLE physiology
Abstract

A letter to the editor is presented in response to the issue on whether insulin-like growth factor-1 (IGF-1) plays a major role in regulating muscle mass during development.

Published
2010

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