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Start Over "Nikolić, Katarina" Topic drug analysis Journal journal of aoac international
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1. Development and Optimization of an HPLC Analysis of Citalopram and Its Four Nonchiral Impurities Using Experimental Design Methodology.

Author

Tadić, Svetlana, Nikolić, Katarina, and Agbaba, Danica

Subjects
*DRUG analysis, *CITALOPRAM, *INDUSTRIAL contamination, *HIGH performance liquid chromatography, *ANALYTICAL chemistry
Abstract

The article presents the study "Development and Optimization of an HPLC Analysis of Citalopram and its Four Nonchiral Impurities Using Experimental Design Methodology," by Svetlana Tadic et al. The influence of experimental conditions buffer pH, flow rate and column temperature on the chromatographic behavior of citalopram and its four impurities was assessed using partial least squares regression (PLSR) and multilayer perceptron (MLP) artificial neural networks (ANNs).

Published
2012
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