1. Effects of growth hormone and feeding level on endocrine measurements, hormone receptors, muscle growth and performance of prepubertal heifers
- Author
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Vestergaard, M., Purup, S., Frystyk, J., Lovendahl, P., Sorensen, M.T., Riiss, P.M., Flint, D.J., and Sejrsen, K.
- Subjects
Heifers -- Food and nutrition ,Heifers -- Physiological aspects ,Somatotropin -- Physiological aspects ,Zoology and wildlife conservation - Abstract
Prepubertal Friesian heifer calves (n = 24, initial BW = 195[+ or -]5 kg) were assigned to a 2 x 2 factorial block design and used to evaluate the effects of daily GH treatment (0 or 15 mg/d) at either a low or a high feeding level in a 5-wk treatment period on endocrine measurements, hormone receptors, muscle growth, and overall performance. In the pretreatment period, a low feeding level was employed for all calves. During the treatment period, animals at the low feeding level had free access to a roughage-based mixture, whereas animals at the high feeding level had free access to a concentrate mixture and were offered 2 kg/ d of the roughage-based mixture. Blood samples were collected weekly starting 3 wk before treatment. Longissimus (LM) and supraspinatus (SS) muscles were obtained at slaughter. Metabolizable energy intake was 81% higher, digestible CP intake was 140% higher, and ADG was 115% higher (all P < 0.001) at the high vs. low feeding level. Feed (DMI, ME, and protein) intake was not affected by GH treatment, but ADG was 18% higher (P < 0.13) in GH-treated than in control heifers at both feeding levels. Although of different magnitudes, the muscle anabolic effects of GH treatment and high vs. low feeding level were additive, and both treatments increased carcass weights (P Key Words: Binding Proteins, Biochemical Receptors, Heifers, Insulin-Like Growth Factor, Plane of Nutrition, Somatotropin
- Published
- 2003