1. How does the Serum Catecholamine Change and Post Transplant Renal Function
- Author
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Liu Binghua, Shi Pengcai, Liu Mengjie, Dai Chenyang, Feng Dan, and Wang yuelan
- Subjects
Creatinine ,Kidney ,Aldosterone ,business.industry ,medicine.medical_treatment ,Renal function ,Nephrectomy ,chemistry.chemical_compound ,Anesthesiology and Pain Medicine ,medicine.anatomical_structure ,chemistry ,Anesthesia ,Renal blood flow ,Blood plasma ,Medicine ,business ,Blood urea nitrogen - Abstract
Objective: To keep different levels of blood pressure and to observe the effects on the posttransplant renal function under general anesthesia. Methods: We selected 20 patients with the renal normal function (group N, n=20) who undergoing live donor nephrectomy under general anesthesia; the renal failure group (group F n=20) who undergoing renal transplantation. Blood pressure, ECG, SpO2, PETCO2, BIS were monitored continuously. Levels of norepinephrine, epinephrine, aldosterone in blood plasma were measured before anesthesia, after anesthesia before skin incision, at the time point of kidney exploration and after nephrectomy 10 min,40 min,120 min or at the renal vascular anastomosis opened for 10 min, 40 min, 120 min and even for 1st, 3rd days after kidney transplant. Meanwhile, we detected the volume of urine, serum concentrations of Cr (Creatinine), BUN (Blood urea nitrogen), cystsin C (CysC) and β2 microglobulin (β2-MG) for group F1(using the vasoactive drug to maintain the SBP 160-140 mmHg) and group F2 (SBP was kept at 139-110 mmHg) at different time points during the donor’s kidney was transplanted. Results: 1. Aldosterone was increased significantly at kidney exploration or the renal vascular anastomosis, comparied to pre-induction (P
- Published
- 2013
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