1. [Tubulo-interstitial nephritis and uveitis (TINU syndrome): a new pediatric case].
- Author
-
Bensmail D, Rossignol I, Tuil E, Sabourin C, Morin Y, and Héron E
- Subjects
- Child, Female, Humans, Remission Induction, Syndrome, Anti-Inflammatory Agents therapeutic use, Nephritis, Interstitial drug therapy, Prednisone therapeutic use, Uveitis drug therapy
- Abstract
TINU is a rare disease of unknown etiology that associates acute tubulointerstitial nephritis and uveitis in a context of systemic symptoms (asthenia, weight loss, fever) and inflammatory biological signs. We report a new case in a 10-year-old girl with unilateral uveopapillitis and renal insufficiency caused by interstitial nephritis (creatininemia: 225 micro mol/l). Complete recovery was obtained with high-dose systemic corticotherapy, with the patient remaining free of disease 2.5 years after the end of treatment. The disappearance of renal lesions was histologically verified.
- Published
- 2003