1. Les gènes qui font l'identité endothéliale
- Author
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Alexandra Le Bras and Fabrice Soncin
- Subjects
Regulation of gene expression ,Aging ,Endothelium ,Receptor Protein-Tyrosine Kinases ,Cell Biology ,Biology ,Molecular biology ,Cell biology ,Gene expression profiling ,medicine.anatomical_structure ,Transcription (biology) ,cardiovascular system ,medicine ,Epigenetics ,Organ Specificity ,Gene - Abstract
The endothelium is a tissue with a distinct identity due to the specific expression of molecular markers by endothelial cells. Further, the endothelium displays a structural heterogeneity illustrated by the expression of specific markers in arteries and in veins. Here, we present a review of the transcriptional and epigenetic mechanisms regulating the expression of the main markers of endothelial cells in man and mouse, demonstrating that there is no common and unique mechanism of specific expression of genes in these cells.
- Published
- 2009
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