1. Waist-to-height ratio is as reliable as biochemical markers to discriminate pediatric insulin resistance.
- Author
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Alvim RO, Zaniqueli D, Neves FS, Pani VO, Martins CR, Peçanha MAS, Barbosa MCR, Faria ER, and Mill JG
- Subjects
- Adolescent, Body Mass Index, Brazil, Child, Cholesterol, HDL blood, Cross-Sectional Studies, Female, Humans, Lipoproteins, HDL blood, Male, Metabolic Syndrome blood, Overweight blood, Overweight physiopathology, Triglycerides blood, Biomarkers analysis, Blood Glucose analysis, Insulin Resistance physiology, Metabolic Syndrome physiopathology, Waist Circumference physiology, Waist-Height Ratio
- Abstract
Objective: Given the importance of incorporating simple and low-cost tools into the pediatric clinical setting to provide screening for insulin resistance, the present study sought to investigate whether waist-to-height ratio is comparable to biochemical markers for the discrimination of insulin resistance in children and adolescents., Methods: This cross-sectional study involved students from nine public schools. In total, 296 children and adolescents of both sexes, aged 8-14 years, composed the sample. Waist-to-height ratio, triglycerides/glucose index, and triglycerides-to-HDL-C ratio were determined according to standard protocols. Insulin resistance was defined as homeostatic model assessment for insulin resistance with cut-off point ≥ 3.16., Results: Age, body mass index, frequency of overweight, waist circumference, waist-to-height ratio, insulin, glucose, homeostatic model assessment for insulin resistance, triglycerides, triglycerides/glucose index, and triglycerides-to-HDL-C were higher among insulin resistant boys and girls. Moderate correlation of all indicators (waist-to-height ratio, triglycerides/glucose index, and triglycerides-to-HDL-C ratio) with homeostatic model assessment for insulin resistance was observed for both sexes. The areas under the receiver operational characteristic curves ware similar between waist-to-height ratio and biochemical markers., Conclusion: The indicators provided similar discriminatory power for insulin resistance. However, taking into account the cost-benefit ratio, we suggest that waist-to-height ratio may be a useful tool to provide screening for insulin resistance in pediatric populations., (Copyright © 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.)
- Published
- 2019
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