1. Reversible anti-TNFα treatment induced dementia: A case report
- Author
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Camille Hou, Marie-Noëlle Osmont, Emmanuel Azzi, Anne Salmon, and Aleth Perdriger
- Subjects
030203 arthritis & rheumatology ,Rapidly progressive dementia ,medicine.medical_specialty ,Ankylosing spondylitis ,business.industry ,Drug-induced dementia ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Internal medicine ,mental disorders ,Etiology ,Medicine ,Dementia ,Tumor necrosis factor alpha ,030212 general & internal medicine ,business - Abstract
We report the first case of a reversible rapidly progressive dementia occurring in a patient with ankylosing spondylitis, a few months after the beginning of a TNFα inhibitor treatment (TNFi). The exhaustive neurologic explorations were negative. No etiology was found to explain dementia. The dementia slowly improved after TNFi withdrawal. The chronology of this observation suggests a responsibility of the TNFi in the dementia manifestations.
- Published
- 2021