Search

Your search keyword '"Hawkins, Cynthia"' showing total 4 results
Start Over Author "Hawkins, Cynthia" Journal jco precision oncology
4 results on '"Hawkins, Cynthia"'

1. Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers Exhibiting Hypermutation: An IRRDC Study.

Author

Henderson, Jacob J., Das, Anirban, Morgenstern, Daniel A., Sudhaman, Sumedha, Bianchi, Vanessa, Chung, Jill, Negm, Logine, Edwards, Melissa, Kram, David E., Osborn, Michael, Hawkins, Cynthia, Bouffet, Eric, Cho, Yoon-Jae, and Tabori, Uri

Subjects
*IMMUNE checkpoint inhibitors, *CANCER treatment
Abstract

Two targets with one arrow: #Immunotherapy as single treatment for synchronous RRD #glioblastoma and #metastatic cancers. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

2. Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers Exhibiting Hypermutation: An IRRDC Study.

Author

Henderson, Jacob J., Das, Anirban, Morgenstern, Daniel A., Sudhaman, Sumedha, Bianchi, Vanessa, Chung, Jill, Negm, Logine, Edwards, Melissa, Kram, David E., Osborn, Michael, Hawkins, Cynthia, Bouffet, Eric, Cho, Yoon-Jae, and Tabori, Uri

Subjects
*IMMUNE checkpoint inhibitors, *CANCER treatment
Abstract

Two targets with one arrow: #Immunotherapy as single treatment for synchronous RRD #glioblastoma and #metastatic cancers. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

3. Upfront Adjuvant Immunotherapy of Replication Repair–Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach.

Author

Larkin, Trisha, Das, Anirban, Bianchi, Vanessa, Sudhaman, Sumedha, Chung, Jiil, Alsafwani, Noor, Negm, Logine, Yachnis, Anthony, Blatt, Jason, Hawkins, Cynthia, Bouffet, Eric, Tabori, Uri, and Gururangan, Sridharan

Subjects
*BRAIN tumors, *PHYSICIANS, *GLIOBLASTOMA multiforme, *IMMUNE checkpoint inhibitors, *MAGNETIC resonance imaging, *SINGLE nucleotide polymorphisms
Abstract

(A) Timeline of first surgery, tumor regrowth, second surgery, initiation of nivolumab, and follow-up. (B) Histopathology confirming glioblastoma and loss of staining of PMS2 and MLH1 in tumor cells only, and retained in normal cells, along with staining retained in tumor cells for MSH2 and MSH6. Pediatric glioblastoma (GBM) accounts for up to 15% of primary CNS neoplasms in children and is the leading cause of death among this group. As family history and clinical phenotypes may be insufficient to uncover RRD in GBM, molecular tumor analysis should be performed in all patients because of the potential therapeutic benefits. [Extracted from the article]

Published
2021
Full Text
View/download PDF

4. Upfront Adjuvant Immunotherapy of Replication Repair–Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach.

Author

Larkin, Trisha, Das, Anirban, Bianchi, Vanessa, Sudhaman, Sumedha, Chung, Jiil, Alsafwani, Noor, Negm, Logine, Yachnis, Anthony, Blatt, Jason, Hawkins, Cynthia, Bouffet, Eric, Tabori, Uri, and Gururangan, Sridharan

Subjects
*BRAIN tumors, *PHYSICIANS, *GLIOBLASTOMA multiforme, *IMMUNE checkpoint inhibitors, *MAGNETIC resonance imaging, *SINGLE nucleotide polymorphisms
Abstract

(A) Timeline of first surgery, tumor regrowth, second surgery, initiation of nivolumab, and follow-up. (B) Histopathology confirming glioblastoma and loss of staining of PMS2 and MLH1 in tumor cells only, and retained in normal cells, along with staining retained in tumor cells for MSH2 and MSH6. As family history and clinical phenotypes may be insufficient to uncover RRD in GBM, molecular tumor analysis should be performed in all patients because of the potential therapeutic benefits. Pediatric glioblastoma (GBM) accounts for up to 15% of primary CNS neoplasms in children and is the leading cause of death among this group. [Extracted from the article]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results