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Start Over Author "Mallon, Kenneth P." Journal jama, the journal of the american medical association
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1. Effectiveness of Live, Attenuated Intranasal Influenza Virus Vaccine in Healthy, Working Adults

Author

Nichol, Kristin L., Mendelman, Paul M., Mallon, Kenneth P., Jackson, Lisa A., Gorse, Geoffrey J., Belshe, Robert B., Glezen, W. Paul, and Wittes, Janet

Subjects
Influenza vaccines -- Evaluation, Intranasal medication -- Evaluation, Influenza -- Prevention
Abstract

An intranasal influenza vaccine appears to effectively reduce the occurrence of influenza-related illness and absenteeism. Researchers assigned 4,561 adults to receive either a live, trivalent intranasal vaccine or a placebo. Vaccination reduced the rate of severe fever by 19% and the rate of fever with upper respiratory illness 24%, compared to the placebo treatment. Vaccinated people missed fewer days of work, had fewer visits to health care providers, and had fewer days of illness.

Published
1999

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