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Your search keyword '"Lemos, James A. de"' showing total 5 results
Start Over Author "Lemos, James A. de" Journal jama, the journal of the american medical association
5 results on '"Lemos, James A. de"'

1. Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes

Author

Briel, Matthias, Schwartz, Gregory G., Thompson, Peter L., Lemos, James A. de, Blazing, Michael A., van Es, Gerrit-Anne, Kayikcioglu, Meral, Arntz, Hans-Richard, Hartog, Frank R. den, Veeger, Nic J.G.M., Colivicchi, Furio, Dupuis, Jocelyn, Okazaki, Shinya, Wright, R. Scott, Bucher, Heiner C., and Nordmann, Alain J.

Subjects
Coronary heart disease -- Care and treatment, Coronary heart disease -- Research, Statins -- Patient outcomes
Abstract

A study to evaluate relevant outcomes of patients from randomized controlled trials comparing early statin therapy with placebo or usual care at 1 and 4 months following acute coronary syndrome (ACS) is illustrated. Based on available evidence it is concluded that initiation of statin therapy within 14 days following onset of ACS does not reduce death, myocardial infarction, or stroke up to 4 months.

Published
2006

2. Prognostic value of serial B-type natriuretic peptide testing during follow-up of patients with unstable coronary artery disease

Author

Morrow, David A., Braunwald, Eugene, Lemos, James A. de, Califf, Robert M., Blazing, Michael A., Fox, Keith A.A., Sabatine, Marc S., White, Harvey D., Murphy, Sabina A., and Jarolim, Petr

Subjects
Natriuretic peptides -- Health aspects, Natriuretic peptides -- Research, Coronary heart disease -- Risk factors, Coronary heart disease -- Patient outcomes
Abstract

A study to determine whether concentrations of B-type natriuretic peptide (BNP) at study entry and at outpatient follow-up at 4 months and 12 months are associated with subsequent clinical outcomes is presented. Serial determinations of BNP levels during outpatient follow-up after acute coronary syndrome (ACS) predict the risk of death or new congestive heart failure (CHF).

Published
2005

3. Early intensive vs a delayed conservative simvastatin strategy in pateints with acute coronary syndromes: Phase Z of the A to Z trial

Author

Lemos, James A. de, White, Harvey D., Blazing, Michael A., Rouleau, Jean-Lucien, Wiviott, Stephen D., Pedersen, Terje, Lewis, Eldrin F., Gardner Laura H., Fox, Keith A. A., Mukherjee, Robin, Ramsey, Karen E., Palmisano, Joanne, Bilheimer, David W., Pfeffer, Marc A., Califf, Robert M., and Braunwald, Eugene

Subjects
Simvastatin -- Dosage and administration, Coronary heart disease -- Diagnosis, Coronary heart disease -- Prevention
Abstract

The early initiation of an intensive statin regimen with delayed inititation of a less intensive regimen in patients with acute coronary syndrome (ACS) is compared. Results reveal that among patients with ACS, the early initiation of an aggressive simvastatin regimen indicated a favorable trend toward reduction of major cardiovascular events.

Published
2004

4. Efficacy and bleeding complications among patients randomized to enoxaparin or unfractionated heparin for antithrombin therapy in non-ST-segment elevation acute coronary syndromes

Author

Petersen, John L., Goodman, Shaun G., Nessel, Christopher C., Mahaffey, Kenneth W., Langer, Anatoly, Harrington, Robert A., Hasselblad, Vic, Blazing, Michael A., Ferguson, James J., Antman, Elliott M., Le-Moigne-Amarani, Anne, Braunwald, Eugene, Lemos, James A. de, and Califf, Robert M.

Subjects
Heparin -- Dosage and administration, Heparin -- Comparative analysis, Enoxaparin -- Dosage and administration, Enoxaparin -- Comparative analysis, Coronary heart disease -- Care and treatment
Abstract

Unstable angina combined with non-ST-segment elevation myocardial infarction (UA/NSTEMI) acute coronary syndromes (ACS) is the most common manifestations of coronary heart disease that lead to death. More than twenty thousand patients were studied across the ACS spectrum, and it was found that enoxaparin is more effective than unfractionated heparin in preventing combined end point of death or myocardial infarction.

Published
2004

5. Safety and efficacy of enoxaparin vs. unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes who receive tirofiban and aspirin

Author

Blazing, Michael A., Ardissino, Diego, Ramsey, Karen E., Braunwald, Eugene, Lemos, James A. de, DiBattiste, Peter M., Gardner, Laura H., Califf, Robert M., White, Harvey D., Palmisano, Joanne, Hasselblad, Vic, Fox, Keith A. A., Bilheimer, David W., Pfeffer, Marc A., Verheugt, Freek W. A., Snapinn, Steven M., and Lewis, Eldrin F.

Subjects
Coronary heart disease -- Care and treatment, Heparin -- Dosage and administration, Heparin -- Comparative analysis, Enoxaparin -- Dosage and administration, Enoxaparin -- Comparative analysis
Abstract

Tests were conducted to check the efficacy of the combination of enoxaparin and tirofiban in comparison with unfractionated heparin and tirofiban in patients with non-ST-elevation acute coronary syndromes (ACS). It was found that in patients receiving tirofiban and aspirin enoxaparin is a good alternative when compared to unfractionated heparin.

Published
2004

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