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Start Over Author "O'BRIEN, STEPHEN J." Topic genes Topic hiv infections Journal jaids: journal of acquired immune deficiency syndromes
1 results on '"O'BRIEN, STEPHEN J."'

1. Effect of Host Genetics on Incidence of HIV Neuroretinal Disorder in Patients With AIDS.

Author

Sezgin, Efe, Hendrickson, Sher L., Jabs, Douglas A., Van Natta, Mark L., Lewis, Richard A., Troyer, Jennifer L., and O'Brien, Stephen J.

Subjects
*HIV-positive persons, *AIDS, *CONTRAST sensitivity (Vision), *GENES, *ANTIVIRAL agents, *HIV infections, *RETINAL degeneration, *HIV, *PATIENTS
Abstract

The article presents a study on the effect of host genetics on human immunodeficiency virus neuroretinal disorder (HIV-NRD) in patients with AIDS. It notes the loss of contrast sensitivity that is sufficient to impair reading speed. It mentions the validated AIDS restriction gene variants in evaluating the effect of host genes on HIV-NRD which has been implicated to influence HIV-1 infection, AIDS progression, therapy response, and antiviral drug metabolism.

Published
2010
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