1. Visualization of Changes in the Choriocapillaris, Choroidal Vessels, and Retinal Morphology After Focal Laser Photocoagulation Using OCT Angiography
- Author
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Jay S. Duker, Caroline R. Baumal, Ricardo N. Louzada, Andre J. Witkin, Eric M. Moult, Emily Cole, ByungKun Lee, Eduardo A. Novais, Nadia K. Waheed, Harvard University--MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology. Research Laboratory of Electronics, Cole, Emily D., Moult, Eric Michael, and Lee, ByungKun
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,genetic structures ,Fundus Oculi ,medicine.medical_treatment ,Retinal Pigment Epithelium ,01 natural sciences ,Macular Edema ,010309 optics ,03 medical and health sciences ,0302 clinical medicine ,Optical coherence tomography ,Ophthalmology ,0103 physical sciences ,medicine ,Humans ,Fluorescein Angiography ,Aged ,Retrospective Studies ,Diabetic Retinopathy ,Laser Coagulation ,Retinal pigment epithelium ,medicine.diagnostic_test ,Choroid ,business.industry ,Fundus photography ,Light Coagulation ,Retinal Vessels ,Diabetic retinopathy ,Anatomy ,medicine.disease ,Fluorescein angiography ,eye diseases ,Capillaries ,Cross-Sectional Studies ,medicine.anatomical_structure ,030221 ophthalmology & optometry ,Female ,sense organs ,business ,Laser coagulation ,Tomography, Optical Coherence ,Follow-Up Studies - Abstract
Purpose: To utilize optical coherence tomography (OCT) and OCT angiography (OCTA) to describe alterations in the retinal and choriocapillaris vasculature following remote laser photocoagulation. Lesions are classified on the basis of choriocapillaris alteration as evaluated on en face OCTA. Methods: This was a retrospective, cross-sectional study analyzing 28 laser photocoagulation scars from 8 patients treated for diabetic macular edema. All eyes were analyzed using a combination of OCTA, en face and cross-sectional OCT, and fundus photography. Two masked readers scored images for alterations at the level of the retinal pigment epithelium (RPE), choroid, and choriocapillaris. Laser photocoagulation lesions were classified as deep if choriocapillaris alteration was present on OCTA; lesions were classified as superficial if no choriocapillaris alteration was present on OCTA. Results: Optical coherence tomography angiography was found to be useful for evaluation of choriocapillaris alteration underlying regions of laser scarring. Of the 28 analyzed laser scars, 13 were classified as superficial and 15 were classified as deep. Conclusions: Optical coherence tomography angiography can be used to visualize choriocapillaris alterations associated with focal laser photocoagulation treatment., Massachusetts Lions Eye Research Fund, Inc., Macular Vision Research Foundation
- Published
- 2016
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